| Size | Price | |
|---|---|---|
| Other Sizes |
| Targets |
7-Methyl-1-naphthyl acetic acid targets plant growth pathways. It is an auxin analog that regulates plant growth and development. It does not have a specific biological target in mammalian systems but is used in plant biology research.
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|---|---|
| ln Vitro |
In vitro, 7-Methyl-1-naphthyl acetic acid is used as a plant growth regulator. It is an auxin analog that affects plant cell elongation and division. Detailed in vitro data in mammalian systems are not reported.
|
| ln Vivo |
In vivo, 7-Methyl-1-naphthyl acetic acid is used in plant biology research to study auxin signaling and plant growth regulation. It is not used as a therapeutic agent in animals. No specific pharmacological activities have been reported.
|
| Enzyme Assay |
Cell-free assays for 7-Methyl-1-naphthyl acetic acid involve auxin activity studies. The compound is tested in plant-based assays to measure its auxin activity, such as the Arabidopsis root elongation assay or the coleoptile curvature test. No mammalian cell-free assays are applicable.
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| Cell Assay |
Cellular assays for 7-Methyl-1-naphthyl acetic acid use plant cells or tissues. The compound is applied to plant tissues, and its effects on cell elongation, division, and gene expression are assessed. No mammalian cellular assays are applicable.
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| Animal Protocol |
In vivo animal studies for 7-Methyl-1-naphthyl acetic acid have not been reported. As a plant growth regulator, it is not used in animal studies. No therapeutic applications have been described.
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| ADME/Pharmacokinetics |
Pharmacokinetic properties of 7-Methyl-1-naphthyl acetic acid are not extensively characterized. As a plant growth regulator, it is not intended for systemic administration in animals. Storage: typically at room temperature.
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| Toxicity/Toxicokinetics |
Comprehensive toxicity data for 7-Methyl-1-naphthyl acetic acid are limited. As a plant growth regulator, it may have low toxicity to mammals. It is for research use only and not approved for clinical use.
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| References | |
| Additional Infomation |
7-Methyl-1-naphthyl acetic acid is a research compound used in plant biology as an auxin analog and plant growth regulator. It is available from chemical suppliers. No clinical applications have been reported.
|
| Molecular Formula |
C13H12O3
|
|---|---|
| Molecular Weight |
216.23
|
| Exact Mass |
216.078
|
| CAS # |
6836-22-2
|
| PubChem CID |
13570105
|
| Appearance |
White to off-white solid powder
|
| Density |
1.2±0.1 g/cm3
|
| Boiling Point |
408.8±20.0 °C at 760 mmHg
|
| Melting Point |
153-154ºC
|
| Flash Point |
160.7±15.3 °C
|
| Vapour Pressure |
0.0±1.0 mmHg at 25°C
|
| Index of Refraction |
1.625
|
| LogP |
2.65
|
| Hydrogen Bond Donor Count |
1
|
| Hydrogen Bond Acceptor Count |
3
|
| Rotatable Bond Count |
3
|
| Heavy Atom Count |
16
|
| Complexity |
252
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
O(C([H])([H])[H])C1C([H])=C([H])C2C([H])=C([H])C([H])=C(C([H])([H])C(=O)O[H])C=2C=1[H]
|
| InChi Key |
GJPYHKXILUFWKV-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C13H12O3/c1-16-11-6-5-9-3-2-4-10(7-13(14)15)12(9)8-11/h2-6,8H,7H2,1H3,(H,14,15)
|
| Chemical Name |
2-(7-methoxynaphthalen-1-yl)acetic acid
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
DMSO: ~100 mg/mL (~462.5 mM; with ultrasonication)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 5 mg/mL (23.12 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween-80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), Clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of DMSO stock solution (50.0 mg/mL) to 400 μL of PEG300 and mix well; then add 50 μL of Tween-80 and mix well; finally add 450 μL of physiological saline and adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 5 mg/mL (23.12 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), Clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of DMSO stock solution (50.0 mg/mL) to 900 μL of corn oil and mix well. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.6247 mL | 23.1235 mL | 46.2471 mL | |
| 5 mM | 0.9249 mL | 4.6247 mL | 9.2494 mL | |
| 10 mM | 0.4625 mL | 2.3124 mL | 4.6247 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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