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D-Glucose-13C6

Alias: Glucose-13C6; D-(+)-Glucose-13C6; Dextrose-13C6
Cat No.:V133627 Purity: ≥98%
D-Glucose-13C6 is a stable isotope-labeled analog of D-glucose.
D-Glucose-13C6
D-Glucose-13C6 Chemical Structure CAS No.: 110187-42-3
Product category: Endogenous Metabolite
This product is for research use only, not for human use. We do not sell to patients.
Size Price Stock Qty
50mg
100mg
250mg
1g
5g
10g
Other Sizes

Other Forms of D-Glucose-13C6:

  • Periplanetin (1-O-benzoyl-BETA-D-glucose ester)
  • Alpha-D-Glucose 1,6-bisphosphate tetrapotassium
  • alpha-D-glucose
  • D-Glucose-13C (Glucose-13C; D-(+)-Glucose-13C; Dextrose-13C)
  • D-Glucose-13C-5 (Glucose 13C-5)
Official Supplier of:
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Top Publications Citing lnvivochem Products
Product Description
D-Glucose-13C6 is a stable isotopic analog of D-glucose. D-glucose-13C6 can be used as a metabolic tracer to track glucose-related anabolism and catabolism, or as a synthetic raw material, a minimal culture medium reagent, and an internal standard.
Biological Activity I Assay Protocols (From Reference)
ln Vivo
D-glucose-13C6 (0.1 g dissolved in 25 g carrot medium for eggs, or dissolved with 1 g 99.5% sucrose in 15 mL water for adults) can slightly reduce the hatching rate of eggs, larval development, adult emergence rate, mating period and mating number of Mediterranean fruit flies [1].
Animal Protocol
Animal/Disease Models:Mediterranean Fruit Fly [1]
Doses: 0.1 g
Route of Administration: Egg culture: Added to 25 g carrot culture medium; Adult culture: Dissolved in 15 ml water with 1 g 99.5% sucrose.
Experimental Results: Hatching rate decreased from 85% to 79%, adult emergence rate decreased from 57% to 50.6%, and development time was prolonged. The number of matings and mating time of marked larvae decreased slightly, while the mating time of adults decreased more significantly.
References

[1]. Stable isotope labelling of Ceratitis capitata. Plant Protect. Sci.2019;55(1):54-60.

[2]. Synthesis of methyl 4'-O-methyl-beta-D-cellobioside-13C12 from D-glucose-13C6. Part 2: solid-state NMR studies. Carbohydr Res. 2007 Jan 15;342(1):65-70.

[3]. A convenient LC-MS method for assessment of glucose kinetics in vivo with D-[13C6]glucose as a tracer. Clin Chem. 2009 Mar;55(3):527-32.

These protocols are for reference only. InvivoChem does not independently validate these methods.
Physicochemical Properties
Molecular Formula
13C6H12O6
Molecular Weight
186.11
CAS #
110187-42-3
Related CAS #
D-Glucose
Appearance
White to off-white solid
SMILES
O=[13CH][13C@@H]([13C@H]([13C@@H]([13C@@H]([13CH2]O)O)O)O)O
Synonyms
Glucose-13C6; D-(+)-Glucose-13C6; Dextrose-13C6
HS Tariff Code
2934.99.9001
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Note: (1). 本产品在运输和储存过程中需避光(避免光照)。  (2). 请将本产品存放在密封且受保护的环境中(例如氮气下),避免暴露在潮湿环境中。
Shipping Condition
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
Solubility Data
Solubility (In Vitro)
H2O : ~100 mg/mL (~537.32 mM; with sonication)
Solubility (In Vivo)
Solubility in Formulation 1: 100 mg/mL (537.32 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), Clear solution; Need ultrasonic.

 (Please use freshly prepared in vivo formulations for optimal results.)
Preparing Stock Solutions 1 mg 5 mg 10 mg
1 mM 5.3732 mL 26.8658 mL 53.7317 mL
5 mM 1.0746 mL 5.3732 mL 10.7463 mL
10 mM 0.5373 mL 2.6866 mL 5.3732 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.

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Note: Chemical formula is case sensitive: C12H18N3O4  c12h18n3o4
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In vivo Formulation Calculator (Clear solution)
Step 1: Enter information below (Recommended: An additional animal to make allowance for loss during the experiment)
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Calculation results

Working concentration mg/mL;

Method for preparing DMSO stock solution mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation:Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
             (2) Be sure to add the solvent(s) in order.

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