| Size | Price | Stock | Qty |
|---|---|---|---|
| 10mg |
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| 50mg |
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| 100mg | |||
| Other Sizes |
| Targets |
Prodlure does not have a pharmacological target in mammals. Its primary target is the olfactory receptors of insects, specifically male Spodoptera littoralis moths, where it acts as a sex pheromone to attract males for mating. The compound is used as an insect attractant in pest management strategies. Its mechanism of action involves binding to insect olfactory receptors and triggering behavioral responses.
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|---|---|
| ln Vitro |
The adult female Dioryctria mendacella's pheromone gland extract contains at least ten times as much (Z,Z,Z,Z,Z)-3,6,9,12, 15-25 Carbopentene (ZZZZZ3,6,9,12,15-25:H) as well as (9Z,11E)-Prodlure[1].
Prodlure is not a pharmacologically active compound in mammals and therefore does not have in vitro activity in mammalian systems. Its activity is assessed in insect behavioral assays, where it attracts male Spodoptera littoralis moths. The compound's efficacy as a pheromone is measured by its ability to attract male moths in field or laboratory settings. |
| ln Vivo |
Prodlure is used in field applications as an insect attractant for pest management. It is a major component of the sex pheromone of female Spodoptera littoralis and is effective in attracting male moths for monitoring and control purposes. However, in vivo data in mammals are not applicable, as the compound is not used as a drug.
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| Enzyme Assay |
In vitro enzyme/receptor binding assays are not applicable for Prodlure in the context of mammalian pharmacology, as it is an insect pheromone. The compound's activity is assessed in insect behavioral assays or electrophysiological assays measuring olfactory receptor responses.
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| Cell Assay |
Cellular assays are not typically performed for Prodlure in mammalian systems, as it is an insect pheromone. Its activity is assessed in insect behavioral assays or electrophysiological assays measuring olfactory receptor responses in insect antennae.
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| Animal Protocol |
In vivo animal studies are not applicable for Prodlure in the context of mammalian pharmacology, as it is an insect pheromone. The compound is used in field studies to attract male Spodoptera littoralis moths for pest management purposes.
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| ADME/Pharmacokinetics |
Prodlure has a molecular formula of C16H28O2 and a molecular weight that is not specified in the available literature. It has a melting point of <25°C, a boiling point of 378.0°C at 760 Torr, and a density of 0.890 g/cm3 at 20°C. However, pharmacokinetic parameters are not applicable, as the compound is not a drug.
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| Toxicity/Toxicokinetics |
Prodlure is classified as a pheromone and is not intended for human consumption. Comprehensive toxicology data for this compound are not extensively reported. As an insect attractant used in agricultural settings, it is not associated with significant toxicity in mammals at the levels used for pest management.
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| References | |
| Additional Infomation |
9Z,11E-Tetradecadienyl acetate is a carboxylic acid ester. It has been reported that this product exists in Heterostelium tenuissimum, and relevant data are available for reference.
Prodlure is a sex pheromone component of female Spodoptera littoralis, the Egyptian cotton leafworm. It is used as an insect attractant, repellent, and chemosterilant in pest management and agricultural research. The compound is also known as (9Z,11E)-9,11-Tetradecadien-1-yl acetate and has synonyms such as Litlure A and Ferodin SL. It is not a drug and is not approved for clinical use. |
| Molecular Formula |
C16H28O2
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|---|---|
| Molecular Weight |
252.39200
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| Exact Mass |
252.209
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| CAS # |
50767-79-8
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| PubChem CID |
6441057
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| Appearance |
Colorless to light yellow liquid
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| Density |
0.89g/cm3
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| Boiling Point |
378ºC at 760 mmHg
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| Flash Point |
107.1ºC
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| Index of Refraction |
1.463
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| LogP |
4.802
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
2
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| Rotatable Bond Count |
12
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| Heavy Atom Count |
18
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| Complexity |
242
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| Defined Atom Stereocenter Count |
0
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| SMILES |
CC/C=C/C=C\CCCCCCCCOC(C)=O
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| InChi Key |
RFEQLTBBKNKGGJ-DEQVHDEQSA-N
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| InChi Code |
InChI=1S/C16H28O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-18-16(2)17/h4-7H,3,8-15H2,1-2H3/b5-4+,7-6-
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| Chemical Name |
[(9Z,11E)-tetradeca-9,11-dienyl] acetate
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO : ~100 mg/mL (~396.21 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (9.91 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: 2.5 mg/mL (9.91 mM) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), suspension solution; with ultrasonication. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. View More
Solubility in Formulation 3: ≥ 2.5 mg/mL (9.91 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.9621 mL | 19.8106 mL | 39.6212 mL | |
| 5 mM | 0.7924 mL | 3.9621 mL | 7.9242 mL | |
| 10 mM | 0.3962 mL | 1.9811 mL | 3.9621 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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