Poncirin

Alias: Poncirin
Cat No.:V34291 Purity: ≥98%
Poncirin is extracted from clover and has anti~inflammatory activity.
Poncirin Chemical Structure CAS No.: 14941-08-3
Product category: Natural Products
This product is for research use only, not for human use. We do not sell to patients.
Size Price Stock Qty
1mg
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Product Description
Poncirin is extracted from clover and has anti~inflammatory activity. Poncirin significantly reduced mechanical hyperalgesia and allodynia in a mouse model of complete Freund's adjuvant (CFA)-induced inflammatory pain.
Biological Activity I Assay Protocols (From Reference)
ln Vivo
Citrus aurantium (ip; 30 mg/kg) significantly decreased visceral pain caused by acetic acid and tonic pain induced by formalin in the complete Freund's adjuvant (CFA)-induced inflammatory pain model. pain-related behavior[1].
References
[1]. Ling H, et al. Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells.Mol Carcinog. 2009 Jun;48(6):498-507.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Physicochemical Properties
Molecular Formula
C28H34O14
Molecular Weight
594.5612
Exact Mass
594.19
Elemental Analysis
C, 56.56; H, 5.76; O, 37.67
CAS #
14941-08-3
Appearance
Solid powder
SMILES
C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=CC(=C4C(=O)C[C@H](OC4=C3)C5=CC=C(C=C5)OC)O)CO)O)O)O)O)O
InChi Key
NLAWPKPYBMEWIR-SKYQDXIQSA-N
InChi Code
InChI=1S/C28H34O14/c1-11-21(32)23(34)25(36)27(38-11)42-26-24(35)22(33)19(10-29)41-28(26)39-14-7-15(30)20-16(31)9-17(40-18(20)8-14)12-3-5-13(37-2)6-4-12/h3-8,11,17,19,21-30,32-36H,9-10H2,1-2H3/t11-,17-,19+,21-,22+,23+,24-,25+,26+,27-,28+/m0/s1
Chemical Name
(2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one
Synonyms
Poncirin
HS Tariff Code
2934.99.9001
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Shipping Condition
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
Solubility Data
Solubility (In Vitro)
DMSO : ~100 mg/mL (~168.19 mM)
Preparing Stock Solutions 1 mg 5 mg 10 mg
1 mM 1.6819 mL 8.4096 mL 16.8192 mL
5 mM 0.3364 mL 1.6819 mL 3.3638 mL
10 mM 0.1682 mL 0.8410 mL 1.6819 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.

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