| Size | Price | |
|---|---|---|
| Other Sizes |
| Targets |
Polyvinyl alcohol does not have a specific biological target as it is a synthetic polymer. It is used as a biomaterial, emulsifier, and thickening agent. It is used in pharmaceutical applications as a binding agent and in the formulation of drug delivery systems.
|
|---|---|
| ln Vitro |
There are no in vitro biological activities for Polyvinyl alcohol as a drug. It is used as a polymer in various applications, including as a coating and thickening agent.
|
| ln Vivo |
There are no in vivo applications for Polyvinyl alcohol as a therapeutic agent. It is used in pharmaceutical formulations as an excipient.
|
| Enzyme Assay |
There are no in vitro enzyme/receptor binding assays for Polyvinyl alcohol as it is not a biologically active compound. It is used as a polymer in biochemical applications.
|
| Cell Assay |
There are no in vitro cell-based assays for Polyvinyl alcohol as it is not a biologically active compound. It is used as a coating for cell culture surfaces.
|
| Animal Protocol |
There are no in vivo animal experimental protocols for Polyvinyl alcohol as it is not a therapeutic agent. It is used as an excipient in pharmaceutical formulations.
|
| ADME/Pharmacokinetics |
Pharmacokinetic properties of Polyvinyl alcohol are not characterized as it is not a drug. It is water-soluble.
|
| Toxicity/Toxicokinetics |
No toxicity data for Polyvinyl alcohol are available. It is generally considered non-toxic.
|
| References | |
| Additional Infomation |
Polyvinyl alcohol is a water-soluble synthetic resin. It is used in adhesives, coatings, and as a thickening or binding agent. Its CAS number is 9002-89-5.
|
| Molecular Formula |
C2H4O
|
|---|---|
| Molecular Weight |
44.0526
|
| Exact Mass |
44.026
|
| CAS # |
9002-89-5
|
| Appearance |
White to off-white solid powder
|
| Density |
0.8±0.1 g/cm3
|
| Boiling Point |
23.5±13.0 °C at 760 mmHg
|
| Melting Point |
230-240ºC
|
| Flash Point |
-28.3±12.8 °C
|
| Vapour Pressure |
811.9±0.0 mmHg at 25°C
|
| Index of Refraction |
1.381
|
| LogP |
0.26
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
DMSO : ~50 mg/mL
H2O : < 0.1 mg/mL |
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (Infinity mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 22.7015 mL | 113.5074 mL | 227.0148 mL | |
| 5 mM | 4.5403 mL | 22.7015 mL | 45.4030 mL | |
| 10 mM | 2.2701 mL | 11.3507 mL | 22.7015 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
