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    Polymyxin B sulphate
    Polymyxin B sulphate

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    This product is for research use only, not for human use. We do not sell to patients.
    Number: - + Pieces(InventoryPieces)
    InvivoChem Cat #: V1863
    CAS #: 1405-20-5Purity ≥98%

    Description: Polymyxin B (also known as Aerosporin, PMB, Poly-RX) is an antibiotic and a cationic surfactant primarily used for resistant gram-negative infections. Polymyxin B sulfate is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic.

    References: Am J Physiol. 1991 Jul;261(1 Pt 2):R26-31; Eur J Pharmacol. 1991 May 25;207(1):17-22.

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    Molecular Weight (MW)1301.56 
    FormulaC56H98N16O13.H2SO4 
    CAS No.1405-20-5 
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Solubility (In vitro)DMSO: <1 mg/mL
    Water: 100 mg/mL (76.83 mM)
    Ethanol: <1 mg/mL
    Solubility (In vivo)Chemical Name: N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18R,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide;sulfuric acidSMILES Code: CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CCN)CC2=CC=CC=C2)CC(C)C)CCN)CCN)C(C)O.OS(=O)(=O)O
    SynonymsAerosporin, PMB, Poly-RX; KS-1428; KS 1428; KS1428; Polymyxin B Sulfate; Polymyxin B;


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