| Size | Price | Stock | Qty |
|---|---|---|---|
| 100mg |
|
||
| 250mg |
|
||
| 500mg |
|
||
| Other Sizes |
| Toxicity/Toxicokinetics |
Toxicity Data
LC50 (Rat) > 3,710 mg/m³/4H |
|---|---|
| References | |
| Additional Infomation |
Oxyfluorfen is an orange crystalline solid, non-corrosive, used as a herbicide. Oxyfluorfen is an aromatic ether with herbicidal and protoporphyrinogen oxidase (EC 1.3.3.4) inhibitory effects. Oxyfluorfen is a selective pre- and post-emergence herbicide used to control certain annual broadleaf and grass weeds on vegetables, fruits, cotton, ornamental plants, and non-cultivated land. It is a contact herbicide and requires light to act on target plants. Mechanism of Action: Diphenyl ether herbicides are potent inhibitors of protoporphyrinogen oxidase, a membrane-bound enzyme involved in the biosynthesis of heme and chlorophyll. Diphenyl ether herbicides exert their phytotoxic effects by inhibiting protoporphyrinogen oxidase, thus preventing chlorophyll formation. This enzyme is the final step in the common biosynthesis of chlorophyll and heme.
|
| Molecular Formula |
C15H11CLF3NO4
|
|---|---|
| Molecular Weight |
361.7
|
| Exact Mass |
361.032
|
| CAS # |
42874-03-3
|
| PubChem CID |
39327
|
| Appearance |
Off-white to light yellow solid powder
|
| Density |
1.4±0.1 g/cm3
|
| Boiling Point |
387.1±42.0 °C at 760 mmHg
|
| Melting Point |
83-84°C
|
| Flash Point |
187.9±27.9 °C
|
| Vapour Pressure |
0.0±0.9 mmHg at 25°C
|
| Index of Refraction |
1.536
|
| LogP |
4.34
|
| Hydrogen Bond Donor Count |
0
|
| Hydrogen Bond Acceptor Count |
7
|
| Rotatable Bond Count |
4
|
| Heavy Atom Count |
24
|
| Complexity |
432
|
| Defined Atom Stereocenter Count |
0
|
| InChi Key |
OQMBBFQZGJFLBU-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3
|
| Chemical Name |
2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene
|
| Synonyms |
Galigan; Boxer; Oxyfluorfen
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
DMSO : ~100 mg/mL (~276.47 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (6.91 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.7647 mL | 13.8236 mL | 27.6472 mL | |
| 5 mM | 0.5529 mL | 2.7647 mL | 5.5294 mL | |
| 10 mM | 0.2765 mL | 1.3824 mL | 2.7647 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
