| Size | Price | Stock | Qty |
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| 1mg |
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| 5mg |
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| 10mg |
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| Other Sizes |
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| ln Vitro |
TAP1-I- and C57BL/6 macrophages can process Crl-OVA and full-length OVA in distinct cellular compartments. Additionally, TAP-independent processing of MHC class I presentation is influenced by the protein background of the OVA epitope, OVA peptide (257-264). The TAP transporter presents the epitope in several ways: While the OVA peptide (257–264) in full-length ovalbumin is highly dependent on the TAP transporter, regardless of whether the native protein is coupled to polystyrene or the recombinant OVA is expressed in bacteria, the OVA peptide (257–264) in the MBPCrl-OVA or Crl-OVA bacterial fusion protein depends on the TAP transporter [1].
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| References |
| Molecular Formula |
C49H76F6N10O17
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|---|---|
| Molecular Weight |
1191.17497444153
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| Exact Mass |
1076.536
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| CAS # |
1262751-08-5
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| Related CAS # |
OVA Peptide(257-264);138831-86-4;OVA Peptide(257-264) acetate salt
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| PubChem CID |
71311993
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| Appearance |
White to off-white solid powder
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| Hydrogen Bond Donor Count |
14
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| Hydrogen Bond Acceptor Count |
20
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| Rotatable Bond Count |
33
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| Heavy Atom Count |
75
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| Complexity |
1780
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| Defined Atom Stereocenter Count |
10
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| SMILES |
FC(C(=O)O)(F)F.FC(C(=O)O)(F)F.O=C([C@H]([C@@H](C)CC)NC([C@H](CO)N)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)O)CC(C)C)=O)CCCCN)=O)CCC(=O)O)=O)CC1C=CC=CC=1)=O)CC(N)=O)=O)[C@@H](C)CC
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| InChi Key |
BRUCWCULSHVYBQ-VPZPQSBKSA-N
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| InChi Code |
InChI=1S/C45H74N10O13.C2HF3O2/c1-7-25(5)36(55-44(66)37(26(6)8-2)54-38(60)28(47)23-56)43(65)52-32(22-34(48)57)42(64)51-31(21-27-14-10-9-11-15-27)41(63)50-30(17-18-35(58)59)40(62)49-29(16-12-13-19-46)39(61)53-33(45(67)68)20-24(3)4;3-2(4,5)1(6)7/h9-11,14-15,24-26,28-33,36-37,56H,7-8,12-13,16-23,46-47H2,1-6H3,(H2,48,57)(H,49,62)(H,50,63)(H,51,64)(H,52,65)(H,53,61)(H,54,60)(H,55,66)(H,58,59)(H,67,68);(H,6,7)/t25-,26-,28-,29-,30-,31-,32-,33-,36-,37-;/m0./s1
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| Chemical Name |
(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S,3S)-2-[[(2S,3S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-methylpentanoyl]amino]-3-methylpentanoyl]amino]-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]-4-carboxybutanoyl]amino]hexanoyl]amino]-4-methylpentanoic acid;2,2,2-trifluoroacetic acid
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO : ~125 mg/mL (~116.05 mM)
H2O : ~50 mg/mL (~46.42 mM) |
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| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.08 mg/mL (1.93 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 20.8 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 0.8395 mL | 4.1975 mL | 8.3950 mL | |
| 5 mM | 0.1679 mL | 0.8395 mL | 1.6790 mL | |
| 10 mM | 0.0840 mL | 0.4198 mL | 0.8395 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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