| Size | Price | Stock | Qty |
|---|---|---|---|
| 5mg |
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| 10mg |
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| 100mg | |||
| Other Sizes |
| References | |
|---|---|
| Additional Infomation |
Reports indicate that resorcinol gentiobiglycoside has been found in cashews (Semecarpus anacardium) and curculigo (Curculigo orchioides), and relevant data are available for reference.
Orcinol gentiobioside was isolated from the fraction eluted with 20% aqueous MeOH from a D101 resin column, followed by repeated purification on Sephadex LH-20 chromatography (EtOH-H2O gradient, then MeOH-H2O, and EtOH-acetone). It was obtained as a white amorphous powder (18 mg). Its structure was elucidated using 1H NMR (400 MHz, CD3OD), 13C NMR (100 MHz, CD3OD), and FAB-MS (m/z 447 [M-H]+). This compound was isolated for the first time from Curculigo breviscapa. [1] |
| Molecular Formula |
C19H28O12
|
|---|---|
| Molecular Weight |
448.4184
|
| Exact Mass |
448.158
|
| CAS # |
164991-86-0
|
| PubChem CID |
10411370
|
| Appearance |
White to off-white solid
|
| Density |
1.6±0.1 g/cm3
|
| Boiling Point |
781.5±60.0 °C at 760 mmHg
|
| Melting Point |
117-120℃
|
| Flash Point |
426.5±32.9 °C
|
| Vapour Pressure |
0.0±2.8 mmHg at 25°C
|
| Index of Refraction |
1.667
|
| Source |
Originated from plants: Amaryllidaceae Curculigo orchioides Gaertn.
|
| LogP |
-1.81
|
| Hydrogen Bond Donor Count |
8
|
| Hydrogen Bond Acceptor Count |
12
|
| Rotatable Bond Count |
6
|
| Heavy Atom Count |
31
|
| Complexity |
566
|
| Defined Atom Stereocenter Count |
10
|
| SMILES |
O1C([H])(C([H])(C([H])(C([H])(C1([H])C([H])([H])OC1([H])C([H])(C([H])(C([H])(C([H])(C([H])([H])O[H])O1)O[H])O[H])O[H])O[H])O[H])O[H])OC1C([H])=C(C([H])=C(C([H])([H])[H])C=1[H])O[H]
|
| InChi Key |
XZPNBJLXZMBECP-SKYGPZSASA-N
|
| InChi Code |
InChI=1S/C19H28O12/c1-7-2-8(21)4-9(3-7)29-19-17(27)15(25)13(23)11(31-19)6-28-18-16(26)14(24)12(22)10(5-20)30-18/h2-4,10-27H,5-6H2,1H3/t10-,11-,12-,13-,14+,15+,16-,17-,18-,19-/m1/s1
|
| Chemical Name |
(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(3-hydroxy-5-methylphenoxy)oxan-2-yl]methoxy]oxane-3,4,5-triol
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture and light. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
Ethanol: ~25 mg/mL (~55.8 mM; with ultrasonication)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 1.25 mg/mL (2.79 mM) (saturation unknown) in 10% EtOH + 40% PEG300 + 5% Tween-80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), Clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of ethanol stock solution (12.5 mg/mL) to 400 μL of PEG300 and mix well; then add 50 μL of Tween-80 and mix well; finally add 450 μL of physiological saline and adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 1.25 mg/mL (2.79 mM) (saturation unknown) in 10% EtOH + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), Clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of ethanol stock solution (12.5 mg/mL) to 900 μL of 20% SBE-β-CD saline and mix well. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.2301 mL | 11.1503 mL | 22.3005 mL | |
| 5 mM | 0.4460 mL | 2.2301 mL | 4.4601 mL | |
| 10 mM | 0.2230 mL | 1.1150 mL | 2.2301 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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