| Size | Price | Stock | Qty |
|---|---|---|---|
| 100mg |
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| 500mg |
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| Other Sizes |
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| References |
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|---|---|
| Additional Infomation |
1-monolauroylglycerol is a 1-monoglyceride with dodecanoyl (lauroyl) as the acyl group. It is a 1-monoglyceride and a dodecanoate ester.
See also: Glycerides, C12-18 (annotation moved to); Glyceryl Laurate (annotation moved to). |
| Molecular Formula |
C15H30O4
|
|---|---|
| Molecular Weight |
274.4
|
| Exact Mass |
274.214
|
| CAS # |
142-18-7
|
| Related CAS # |
Monolaurin-d23
|
| PubChem CID |
14871
|
| Appearance |
White to off-white <52°C powder,>52°C liquid
|
| Density |
1.0±0.1 g/cm3
|
| Boiling Point |
397.4±22.0 °C at 760 mmHg
|
| Melting Point |
63ºC
|
| Flash Point |
135.6±15.8 °C
|
| Vapour Pressure |
0.0±2.1 mmHg at 25°C
|
| Index of Refraction |
1.467
|
| LogP |
4.04
|
| Hydrogen Bond Donor Count |
2
|
| Hydrogen Bond Acceptor Count |
4
|
| Rotatable Bond Count |
14
|
| Heavy Atom Count |
19
|
| Complexity |
206
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
O(C([H])([H])C([H])(C([H])([H])O[H])O[H])C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=O
|
| InChi Key |
ARIWANIATODDMH-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C15H30O4/c1-2-3-4-5-6-7-8-9-10-11-15(18)19-13-14(17)12-16/h14,16-17H,2-13H2,1H3
|
| Chemical Name |
2,3-dihydroxypropyl dodecanoate
|
| Synonyms |
Glyceryl monolaurate1-Monolaurin Lauricidin L1475 L 1475 L-1475
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
DMSO : ~12.5 mg/mL (~45.55 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 1.25 mg/mL (4.56 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 12.5 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: 1.25 mg/mL (4.56 mM) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), suspension solution; with ultrasonication. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 12.5 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. View More
Solubility in Formulation 3: ≥ 1.25 mg/mL (4.56 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.6443 mL | 18.2216 mL | 36.4431 mL | |
| 5 mM | 0.7289 mL | 3.6443 mL | 7.2886 mL | |
| 10 mM | 0.3644 mL | 1.8222 mL | 3.6443 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
| NCT Number | Recruitment | interventions | Conditions | Sponsor/Collaborators | Start Date | Phases |
| NCT06046937 | COMPLETED | Drug: Monolaurin Drug: Mupirocin ointment |
Bacterial Infections | Victoriano Luna Medical Center | 2023-06-01 | Early Phase 1 |
| NCT05079763 | UNKNOWN STATUS | Other: Bacterial cellulose-monolaurin hydrogel Other: Placebo cream |
Acute Radiation Dermatitis | University of the Philippines | 2021-09-01 | Phase 2 |
| NCT02709005 | COMPLETEDWITH RESULTS | Drug: 5% Monolaurin Vaginal Gel Other: Placebo |
Bacterial Vaginosis | National Institute of Allergy and Infectious Diseases (NIAID) | 2016-04-14 | Phase 2 |
| NCT00004690 | COMPLETED | Drug: monolaurin cream | Ichthyosis | Cellegy Pharmaceuticals | 1996-09 | Phase 3 |
| NCT00913523 | COMPLETEDWITH RESULTS | Device: Experimental - Tampon with GML Device: Sham Control - Tampons without GML |
Vaginal Microflora | 公司 | 2009-01 | Not Applicable |
Products are for research use only; We do not sell to patients
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