| Size | Price | Stock | Qty |
|---|---|---|---|
| 1g |
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| Other Sizes |
| Targets |
Maltose does not have a specific therapeutic target but is a substrate for the enzyme maltase. Maltase hydrolyzes maltose into two glucose molecules, which are then absorbed and used for energy. This disaccharide is also a product of starch digestion and is an important energy source. In research, it is used to study carbohydrate digestion and metabolism.
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|---|---|
| ln Vitro |
Maltose is an essential structural motif of starch and a two-unit member of the amylose homology series. Maltose is produced when beta-amylase breaks down starch by removing two glucose units at a time. A α (1→6) bond connects the two glucose molecules in iso-maltose.
In vitro, Maltose is used as a substrate in assays to measure the activity of maltase and other α-glucosidases. It is also used as a component in cell culture media, although glucose is more commonly used. Its primary role is as a nutrient and a research tool for studying carbohydrate metabolism. |
| ln Vivo |
In vivo, Maltose is digested by maltase in the small intestine to release glucose, which is then absorbed into the bloodstream. It is an important source of energy in the diet. It is also used in clinical nutrition as a component of oral rehydration solutions and infant formulas.
|
| Enzyme Assay |
In vitro non-cell enzyme assays for Maltose involve measuring the activity of maltase or other α-glucosidases. The disaccharide is incubated with the enzyme, and the release of glucose is measured using a glucose assay, such as the glucose oxidase-peroxidase method.
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| Cell Assay |
In vitro cell-based assays for Maltose are not common, as glucose is the primary sugar used in cell culture. However, it can be used in studies of intestinal epithelial cells to study carbohydrate absorption and digestion.
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| Animal Protocol |
In vivo animal studies for Maltose are typically nutritional studies. Animals are fed diets containing maltose, and its effects on blood glucose levels, metabolism, and growth are assessed.
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| ADME/Pharmacokinetics |
Maltose has a molecular weight of 342.30 g/mol and a molecular formula of C₁₂H₂₂O₁₁. It is a white crystalline powder. It is soluble in water. It should be stored in a cool, dry place, protected from moisture.
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| Toxicity/Toxicokinetics |
Maltose is generally recognized as safe (GRAS) as a food ingredient. It is non-toxic at normal dietary levels. Excessive consumption may cause gastrointestinal distress, such as diarrhea, in individuals with maltase deficiency.
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| Additional Infomation |
β-Maltose is a maltose with a β-configuration at the reducing end anomeric carbon center. It has anti-aging effects. D-Maltose is a metabolite found in or produced by Escherichia coli (K12 strain, MG1655 strain). Maltose has been reported in hops, Daphnia frenulum, and other organisms with relevant data. It is a dextrorotatory disaccharide produced from malt and starch. It is used as a sweetener and fermentable intermediate in brewing. (Grant and Hack's Dictionary of Chemistry, 5th edition) See also: cellobiose (note moved to); maltose (note moved to).
Maltose is a disaccharide composed of two glucose molecules. It is used as a sweetener and fermentation substrate. It is hydrolyzed to glucose by maltase. It is not a drug and is used as a food ingredient and in research. |
| Molecular Formula |
C12H22O11
|
|---|---|
| Molecular Weight |
342.2965
|
| Exact Mass |
342.116
|
| CAS # |
69-79-4
|
| PubChem CID |
6255
|
| Appearance |
Typically exists as solid at room temperature
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| Density |
1.8±0.1 g/cm3
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| Boiling Point |
667.9±55.0 °C at 760 mmHg
|
| Melting Point |
110ºC
|
| Flash Point |
357.8±31.5 °C
|
| Vapour Pressure |
0.0±4.6 mmHg at 25°C
|
| Index of Refraction |
1.652
|
| LogP |
-3.41
|
| Hydrogen Bond Donor Count |
8
|
| Hydrogen Bond Acceptor Count |
11
|
| Rotatable Bond Count |
4
|
| Heavy Atom Count |
23
|
| Complexity |
382
|
| Defined Atom Stereocenter Count |
10
|
| SMILES |
O([C@]1([H])[C@@]([H])([C@]([H])([C@]([H])([C@@]([H])(C([H])([H])O[H])O1)O[H])O[H])O[H])[C@]1([H])[C@]([H])(C([H])([H])O[H])O[C@]([H])([C@@]([H])([C@@]1([H])O[H])O[H])O[H]
|
| InChi Key |
GUBGYTABKSRVRQ-QUYVBRFLSA-N
|
| InChi Code |
InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5-,6+,7-,8-,9-,10-,11-,12-/m1/s1
|
| Chemical Name |
(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
|
| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
H2O : ~125 mg/mL (~365.18 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 100 mg/mL (292.14 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.9214 mL | 14.6071 mL | 29.2141 mL | |
| 5 mM | 0.5843 mL | 2.9214 mL | 5.8428 mL | |
| 10 mM | 0.2921 mL | 1.4607 mL | 2.9214 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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