| Size | Price | Stock | Qty |
|---|---|---|---|
| 5mg |
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| 10mg |
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| 100mg | |||
| Other Sizes |
| Targets |
Glycoside hydrolases and transferases (e.g., 4-alpha-glucanotransferase). Maltohexaose is a substrate for enzymes that hydrolyze or transfer glycosidic bonds. It is used as an acceptor for quantifying 4-alpha-glucanotransferase activity. It may also interact with other carbohydrate-active enzymes.
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|---|---|
| ln Vitro |
Maltohexaose is used as a substrate in enzymatic assays to measure the activity of carbohydrate-active enzymes. Its primary activity is as a biochemical tool rather than a pharmacologically active compound. It does not have significant biological activity beyond its role as a carbohydrate substrate.
|
| ln Vivo |
No specific in vivo activity data is available for Maltohexaose. As a carbohydrate, it would be metabolized to glucose upon ingestion. It is not used as a therapeutic agent but as a research tool in enzymology and carbohydrate chemistry.
|
| Enzyme Assay |
In vitro enzyme assays using Maltohexaose typically involve measuring the activity of glycoside hydrolases or transferases. For example, 4-alpha-glucanotransferase activity is quantified by measuring the transfer of glucose units to or from maltohexaose as an acceptor or donor. Reaction products are analyzed by HPLC or mass spectrometry.
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| Cell Assay |
The in vitro cellular activity of Maltohexaose is not typically studied, as it is a carbohydrate substrate rather than a pharmacologically active compound. It may be used in cell culture media as a carbohydrate source or in studies of carbohydrate metabolism. Its effects on cellular processes are not well characterized.
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| Animal Protocol |
No specific in vivo animal experimental protocols are available for Maltohexaose. As a carbohydrate, it would be metabolized to glucose upon ingestion. It is not used as a therapeutic agent and is not typically administered in animal studies except as a component of diets or in studies of carbohydrate metabolism.
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| ADME/Pharmacokinetics |
Maltohexaose is a linear oligosaccharide of six glucose units. Molecular formula: C36H62O31, molecular weight: 990.86. Appearance: white powder. Melting point: 204-206degC. Solubility: soluble in water. Storage: under recommended conditions.
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| Toxicity/Toxicokinetics |
No specific toxicological data is available for Maltohexaose. As a carbohydrate, it is expected to have very low toxicity. It is metabolized to glucose and is generally recognized as safe. Standard laboratory safety precautions should be observed.
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| References | |
| Additional Infomation |
α-Malthexasose is a maltohexasose in which the glucose residue at the reducing end exists in the form of a pyranose ring, and the terminal carbon atom has an α configuration. Maltohexasose is a metabolite found or produced in Escherichia coli (strains K12 and MG1655). α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-
Maltohexaose is a linear oligosaccharide of six glucose units used as a substrate in enzymatic assays. It is used in analytical method development and quality control applications. The compound has molecular formula C36H62O31 and molecular weight 990.86. It is not approved for clinical use and is intended for research purposes only. |
| Molecular Formula |
C36H62O31
|
|---|---|
| Molecular Weight |
990.8589
|
| Exact Mass |
990.328
|
| CAS # |
34620-77-4
|
| PubChem CID |
5288409
|
| Appearance |
White to off-white solid powder
|
| Density |
1.87g/cm3
|
| Boiling Point |
1307.8ºC at 760mmHg
|
| Melting Point |
204-206°C
|
| Flash Point |
744.7ºC
|
| Index of Refraction |
1.4365
|
| LogP |
-13.3
|
| Hydrogen Bond Donor Count |
20
|
| Hydrogen Bond Acceptor Count |
31
|
| Rotatable Bond Count |
16
|
| Heavy Atom Count |
67
|
| Complexity |
1510
|
| Defined Atom Stereocenter Count |
30
|
| SMILES |
C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H](O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]4[C@H](O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]5[C@H](O[C@@H]([C@@H]([C@H]5O)O)O[C@@H]6[C@H](O[C@@H]([C@@H]([C@H]6O)O)O)CO)CO)CO)CO)CO)O)O)O)O
|
| InChi Key |
OCIBBXPLUVYKCH-QXVNYKTNSA-N
|
| InChi Code |
InChI=1S/C36H62O31/c37-1-7-13(43)14(44)21(51)32(58-7)64-27-9(3-39)60-34(23(53)16(27)46)66-29-11(5-41)62-36(25(55)18(29)48)67-30-12(6-42)61-35(24(54)19(30)49)65-28-10(4-40)59-33(22(52)17(28)47)63-26-8(2-38)57-31(56)20(50)15(26)45/h7-56H,1-6H2/t7-,8-,9-,10-,11-,12-,13-,14+,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31+,32-,33-,34-,35-,36-/m1/s1
|
| Chemical Name |
(2R,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
H2O : ≥ 250 mg/mL (~252.31 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 20 mg/mL (20.18 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication (<60°C).
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.0092 mL | 5.0461 mL | 10.0922 mL | |
| 5 mM | 0.2018 mL | 1.0092 mL | 2.0184 mL | |
| 10 mM | 0.1009 mL | 0.5046 mL | 1.0092 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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