| Size | Price | Stock | Qty |
|---|---|---|---|
| 250mg |
|
||
| Other Sizes |
| ADME/Pharmacokinetics |
Metabolism/Metabolites
After being absorbed by the roots in plants, they are rapidly metabolized into 3,5-dichloroaniline. |
|---|---|
| Toxicity/Toxicokinetics |
Toxicity Data
LC50 (Rat) > 3,300 mg/m3 Non-human Toxicity Values LD50 (Rats, oral): 3500 mg/kg LD50 (Mice, oral): 4000 mg/kg LD50 (Rats, dermal): >2500 mg/kg LD50 (Rabbit, dermal): >2000 mg/kg For more complete non-human toxicity data for isoproturon (6 in total), please visit the HSDB records page. |
| References |
|
| Additional Infomation |
According to the U.S. Environmental Protection Agency (EPA), iprodione may be carcinogenic. Iprodione is an imidazoline-2,4-dione compound, with its nitrogen atom at position 1 replaced by an N-(isopropyl)formamide group and its nitrogen atom at position 3 replaced by a 3,5-dichlorophenyl group. It is a contact fungicide that inhibits the growth of fungal mycelium and the germination of spores. It is used to control various fungal diseases in fruit and vegetable crops and can also be used as a nematicide. It has the dual effects of being a nematicide and an antifungal pesticide. It is an imidazoline-2,4-dione compound, belonging to the urea, benzene, imidazole, and dichlorophenyldicarboximide fungicides. Iprodione is a hydantoin fungicide. It is used to control crops affected by gray mold, brown rot, sclerotinia rot, and other fungal diseases. It is currently used on a variety of crops: fruits, vegetables, ornamental trees and shrubs, and lawns. It is a contact fungicide that inhibits fungal spore germination and blocks fungal mycelial growth.
Mechanism of Action Inhibits spore germination and fungal mycelial growth. |
| Molecular Formula |
C13H13CL2N3O3
|
|---|---|
| Molecular Weight |
330.17
|
| Exact Mass |
329.033
|
| CAS # |
36734-19-7
|
| Related CAS # |
Iprodione-d5;1215631-57-4
|
| PubChem CID |
37517
|
| Appearance |
White to off-white solid powder
|
| Density |
1.5±0.1 g/cm3
|
| Boiling Point |
481.1±55.0 °C at 760 mmHg
|
| Melting Point |
130-134 °C(lit.)
|
| Flash Point |
244.7±31.5 °C
|
| Vapour Pressure |
0.0±1.3 mmHg at 25°C
|
| Index of Refraction |
1.645
|
| LogP |
2.22
|
| Hydrogen Bond Donor Count |
1
|
| Hydrogen Bond Acceptor Count |
3
|
| Rotatable Bond Count |
2
|
| Heavy Atom Count |
21
|
| Complexity |
448
|
| Defined Atom Stereocenter Count |
0
|
| InChi Key |
ONUFESLQCSAYKA-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C13H13Cl2N3O3/c1-7(2)16-12(20)17-6-11(19)18(13(17)21)10-4-8(14)3-9(15)5-10/h3-5,7H,6H2,1-2H3,(H,16,20)
|
| Chemical Name |
3-(3,5-dichlorophenyl)-2,4-dioxo-N-propan-2-ylimidazolidine-1-carboxamide
|
| Synonyms |
Iprodione Glycophene Glycophen
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
DMSO : ~100 mg/mL (~302.87 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (7.57 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (7.57 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.0287 mL | 15.1437 mL | 30.2874 mL | |
| 5 mM | 0.6057 mL | 3.0287 mL | 6.0575 mL | |
| 10 mM | 0.3029 mL | 1.5144 mL | 3.0287 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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