| Size | Price | |
|---|---|---|
| Other Sizes |
| Targets |
Hydroquinone diacetate does not have a well-defined pharmacological target. As a hydroquinone derivative, it may exhibit antioxidant properties by scavenging free radicals. It may also be hydrolyzed to release hydroquinone, which has melanin synthesis inhibitory activity. Its primary mechanism of action is related to its chemical reactivity as an organic intermediate rather than a specific biological target.
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|---|---|
| ln Vitro |
Hydroquinone diacetate is an OH• inhibitor and an antioxidant. Its activity as a chemical intermediate has been confirmed in various synthetic applications. As a hydroquinone derivative, it may share some of the antioxidant properties of hydroquinone. However, its biological activity is not extensively characterized.
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| ln Vivo |
Hydroquinone diacetate is not used as a drug and does not have well-defined in vivo pharmacological activity. It is a chemical intermediate that is not administered to animals or humans for therapeutic purposes. Its effects are observed in chemical synthesis reactions where it is used as a building block.
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| Enzyme Assay |
Hydroquinone diacetate does not have a typical enzyme/receptor binding assay. Its properties are assessed based on its chemical and physical characteristics, such as purity, melting point, and reactivity. It is not used in standard pharmacological binding assays.
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| Cell Assay |
Hydroquinone diacetate is not typically used in cell-based assays. Its applications are primarily in organic synthesis. The compound's effects on cells are not a primary focus of study, as it is not intended for biological or therapeutic use.
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| Animal Protocol |
Hydroquinone diacetate is not used in animal experiments for pharmacological purposes. Its effects are studied in the context of chemical synthesis. Animal studies are not relevant to its primary applications as a synthetic intermediate.
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| ADME/Pharmacokinetics |
Hydroquinone diacetate has a molecular weight of 194.19 g/mol and a molecular formula of C10H10O4. It is a white to almost white powder or crystal with a melting point of 119.0 to 123.0°C. It is soluble in organic solvents. Its purity is typically ≥98%.
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| Toxicity/Toxicokinetics |
Hydroquinone diacetate is a chemical intermediate that is not intended for human use. Its toxicological profile is not extensively characterized in the available literature. Standard safety precautions should be followed when handling this compound in a laboratory setting.
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| References | |
| Additional Infomation |
Hydroquinone diacetate (1,4-diacetoxybenzene) is a chemical and organic intermediate used in organic synthesis. It is also described as an OH• inhibitor and an antioxidant. The compound is available from various chemical suppliers for research and industrial purposes.
|
| Molecular Formula |
C10H10O4
|
|---|---|
| Molecular Weight |
194.19
|
| Exact Mass |
194.057
|
| CAS # |
1205-91-0
|
| PubChem CID |
71006
|
| Appearance |
White to off-white solid powder
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| Density |
1.2±0.1 g/cm3
|
| Boiling Point |
282.4±23.0 °C at 760 mmHg
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| Melting Point |
121-123 °C(lit.)
|
| Flash Point |
138.6±21.0 °C
|
| Vapour Pressure |
0.0±0.6 mmHg at 25°C
|
| Index of Refraction |
1.506
|
| LogP |
0.98
|
| Hydrogen Bond Donor Count |
0
|
| Hydrogen Bond Acceptor Count |
4
|
| Rotatable Bond Count |
4
|
| Heavy Atom Count |
14
|
| Complexity |
192
|
| Defined Atom Stereocenter Count |
0
|
| InChi Key |
AKOGNYJNGMLDOA-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C10H10O4/c1-7(11)13-9-3-5-10(6-4-9)14-8(2)12/h3-6H,1-2H3
|
| Chemical Name |
(4-acetyloxyphenyl) acetate
|
| Synonyms |
NSC-9277; NSC 9277; Hydroquinone diacetate
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
DMSO : ~50 mg/mL (~257.49 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (12.87 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 5.1496 mL | 25.7480 mL | 51.4960 mL | |
| 5 mM | 1.0299 mL | 5.1496 mL | 10.2992 mL | |
| 10 mM | 0.5150 mL | 2.5748 mL | 5.1496 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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