| Size | Price | Stock | Qty |
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| 50mg |
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| 100mg |
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| 250mg |
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| 500mg |
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| Other Sizes |
| Targets |
As a plant volatile, Farnesene does not have a specific pharmacological target in mammalian systems. It acts as an insect repellent or attractant in plant defense. Farnesene has potential applications in the pharmaceutical and agricultural sectors, where it may have antimicrobial, anti-inflammatory, and antioxidant properties.
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| ln Vitro |
In vitro, Farnesene has been studied for its potential antimicrobial, anti-inflammatory, and antioxidant properties. As a herbivore-induced plant volatile, it mediates plant-insect interactions and enhances insect resistance in various plant species. Detailed in vitro pharmacological activity data in mammalian systems are limited in the available literature.
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| ln Vivo |
In vivo, Farnesene functions as a herbivore-induced plant volatile (HIPV) that enhances insect resistance in many plant species. It plays a crucial role in plant defense mechanisms by mediating plant-insect interactions. Detailed in vivo pharmacological data in animal models are limited in the available literature.
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| Enzyme Assay |
Farnesene's activity as a plant volatile can be studied using plant-insect interaction assays. Typical protocols involve exposing plants to herbivore damage and measuring the emission of farnesene and other volatiles. The compound's effects on insect behavior, such as repellency or attraction, can be assessed using olfactometer or choice assays.
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| Cell Assay |
In vitro cell experiments using Farnesene in mammalian systems are limited in the available literature. The compound is primarily studied in plant systems for its role in herbivore-induced defense responses. Cell-based assays in plant cells may involve measuring the compound's effects on defense gene expression and secondary metabolite production.
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| Animal Protocol |
In vivo animal studies using Farnesene are limited in the available literature. The compound is a natural product primarily studied for its ecological role in plant-insect interactions. Further studies are needed to evaluate its potential pharmacological effects in animal models.
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| ADME/Pharmacokinetics |
Pharmacokinetic data for Farnesene are not available in the searched literature. As a sesquiterpene with a molecular weight of 204.35 g/mol and high lipophilicity, the compound is expected to be rapidly metabolized and cleared. Further pharmacokinetic studies are needed.
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| Toxicity/Toxicokinetics |
Farnesene is considered safe for research use at typical concentrations. As a natural product with a mixture of isomers, it has a favorable safety profile. The compound is used in the fragrance and flavor industries. As a research compound, it is intended for laboratory use only and not for human consumption.
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| Additional Infomation |
It has been reported that 3,7,11-trimethyldodecane-1,3,6,10-tetraene is found in the genera Malus, Artemisia, and other organisms with available data.
Farnesene (mixture of isomers) has a molecular formula of C₁₅H₂₄ and a molecular weight of 204.35 g/mol. Purity is typically 98.01%. The compound is a sesquiterpene natural product and a herbivore-induced plant volatile (HIPV) that plays a crucial role in plant defense mechanisms. |
| Molecular Formula |
C15H24
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|---|---|
| Molecular Weight |
204.351
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| Exact Mass |
204.188
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| CAS # |
125037-13-0
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| Related CAS # |
113244-64-7
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| PubChem CID |
442368
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| Appearance |
Colorless to light yellow liquid（Density：0.877 g/cm3）
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| LogP |
5.201
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
0
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| Rotatable Bond Count |
6
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| Heavy Atom Count |
15
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| Complexity |
270
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| Defined Atom Stereocenter Count |
0
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| SMILES |
CC(=CCCC(=CCC=C(C)C=C)C)C
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| InChi Key |
CXENHBSYCFFKJS-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C15H24/c1-6-14(4)10-8-12-15(5)11-7-9-13(2)3/h6,9-10,12H,1,7-8,11H2,2-5H3
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| Chemical Name |
3,7,11-trimethyldodeca-1,3,6,10-tetraene
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO : ~41.67 mg/mL (~203.91 mM)
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| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.08 mg/mL (10.18 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 20.8 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: 2.08 mg/mL (10.18 mM) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), suspension solution; with ultrasonication. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 20.8 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. View More
Solubility in Formulation 3: ≥ 2.08 mg/mL (10.18 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.8936 mL | 24.4678 mL | 48.9356 mL | |
| 5 mM | 0.9787 mL | 4.8936 mL | 9.7871 mL | |
| 10 mM | 0.4894 mL | 2.4468 mL | 4.8936 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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