| Size | Price | Stock | Qty |
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| 1mg |
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| 5mg |
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| 10mg |
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| 25mg |
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| 100mg | |||
| Other Sizes |
| Targets |
Target: Isotope-Labeled Compounds / Endogenous Metabolite. Ethyl palmitate is a fatty acid ethyl ester that is synthesized in greater amounts than other FAEEs in human subjects after consuming alcohol, making it a biomarker for ethanol consumption.
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|---|---|
| ln Vitro |
Drug compounds have included stable heavy isotopes of carbon, hydrogen, and other elements, mostly as quantitative tracers while the drugs were being developed. Because deuteration may have an effect on a drug's pharmacokinetics and metabolic properties, it is a cause for concern [1].
In vitro, ethyl palmitate-d31 serves as a model compound for identifying other lipids in biological samples. No direct pharmacological activity is reported. It is used in cell culture studies as a tracer to monitor lipid metabolism pathways. |
| ln Vivo |
In vivo, the compound is used in metabolic tracer studies to investigate the absorption, distribution, and transformation of fatty acids. It does not exert pharmacological activity but is a valuable tool for studying lipid metabolism under various conditions.
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| Enzyme Assay |
For cell-free assays: biological samples (plasma, urine, or tissue homogenates) are processed by liquid-liquid extraction, spiked with ethyl palmitate-d31 internal standard, and analyzed by GC-MS or LC-MS. Quantitation is achieved by comparing analyte peak areas to the internal standard.
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| Cell Assay |
No cell-based assays are performed with the labeled standard. The unlabeled compound is used in cosmetic science as a skin- and hair-conditioning agent, but the deuterated form is intended solely for analytical and research applications, not for biological activation studies.
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| Animal Protocol |
No animal studies are conducted directly with the labeled internal standard. For pharmacokinetic studies of unlabeled ethyl palmitate, the compound is administered orally to rodents and the internal standard is used in LC-MS/MS bioanalysis of harvested tissues or plasma to quantify the analyte.
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| ADME/Pharmacokinetics |
PK properties of ethyl palmitate: rapid absorption and metabolism, with hydrolysis to palmitic acid and ethanol. The compound is incorporated into lipid structures and undergoes beta-oxidation. The deuterated standard does not exhibit distinct PK behavior and co-elutes with the unlabeled analyte.
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| Toxicity/Toxicokinetics |
No toxicity data are reported for ethyl palmitate-d31. The unlabeled compound is used as a cosmetic ingredient and is generally regarded as safe for topical use. The deuterated standard is for research use only and not intended for human consumption or therapeutic administration.
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| References |
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| Additional Infomation |
Ethyl palmitate-d31 is a research standard, not a drug. It is not FDA-approved for clinical use. It is widely used in forensic toxicology and clinical research as a biomarker of alcohol consumption and as a reference standard for lipidomics and fatty acid metabolism studies.
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| Molecular Formula |
C18H36O2
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|---|---|
| Molecular Weight |
284.47724
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| Exact Mass |
315.466
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| CAS # |
1215721-57-5
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| Related CAS # |
Ethyl palmitate;628-97-7
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| PubChem CID |
57369475
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| Appearance |
Colorless to light yellow liquid
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| Density |
0.9±0.1 g/cm3
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| Boiling Point |
342.2±0.0 °C at 760 mmHg
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| Flash Point |
149.0±7.5 °C
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| Vapour Pressure |
0.0±0.7 mmHg at 25°C
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| Index of Refraction |
1.443
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| LogP |
8.15
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
2
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| Rotatable Bond Count |
16
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| Heavy Atom Count |
20
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| Complexity |
202
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| Defined Atom Stereocenter Count |
0
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| SMILES |
CCCCCCCCCCCCCCCC(=O)OCC
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| InChi Key |
XIRNKXNNONJFQO-FNWSWSEFSA-N
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| InChi Code |
InChI=1S/C18H36O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20-4-2/h3-17H2,1-2H3/i1D3,3D2,5D2,6D2,7D2,8D2,9D2,10D2,11D2,12D2,13D2,14D2,15D2,16D2,17D2
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| Chemical Name |
ethyl 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13,14,14,15,15,16,16,16-hentriacontadeuteriohexadecanoate
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture and light. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO : ~100 mg/mL (~316.79 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (7.92 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.5152 mL | 17.5759 mL | 35.1519 mL | |
| 5 mM | 0.7030 mL | 3.5152 mL | 7.0304 mL | |
| 10 mM | 0.3515 mL | 1.7576 mL | 3.5152 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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