| Size | Price | Stock | Qty |
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| 50mg |
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| 100mg |
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| 250mg |
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| ln Vitro |
In forensic medicine, 1,2-Indandione (1,2-IND) and 1,8-Diazafloren-9-one (DFO) are used to increase the nutrients found in papillary exudates. Because of its superior boosting qualities, DFO has been the most often utilized medication even though it is more costly and has comparatively higher toxicity when compared to 1,2-IND [1].
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| References | |
| Additional Infomation |
DFO (1,8-diazafluorene-9-one) is a chemical reagent primarily used to enhance latent fingerprints on porous surfaces. Its mechanism of action involves a chemical reaction with the amino acid components of fingerprint residues to form a fluorescent complex that can be developed under specific light sources. In this study, the concentration of the DFO solution was 0.5% (w/v). The DFO solvent system was a mixture of methanol and acetic acid (the volume ratio of the two solvents was not specified in the literature). The specific steps for enhancing latent fingerprints using DFO are as follows: First, fully immerse the porous substrate containing the latent fingerprint (including paper, cardboard, and cotton fabric) in the prepared DFO solution for 10-15 minutes; after immersion, remove the substrate and air dry it at room temperature until no obvious liquid residue remains; then, heat the dried substrate in an oven at 100°C for 5-10 minutes to accelerate the reaction between DFO and amino acids in the fingerprint residue; finally, observe the treated substrate under a 365 nm ultraviolet light source to reveal the enhanced fingerprint. Compared to 1,2-indanedione (another fingerprint enhancer tested in this study), DFO exhibits the following performance differences: on paper and cardboard substrates, DFO produces higher fluorescent fingerprint intensity, resulting in clearer fingerprint patterns; on cotton fabric substrates, the fluorescence intensity of the fingerprint enhanced by DFO is slightly lower than that of 1,2-indanedione. In terms of solution stability, the DFO solution maintained good stability—no obvious precipitation or color change was observed after 7 days of storage at room temperature, while the 1,2-indanedione solution showed slight precipitation during the same storage period [1].
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| Molecular Formula |
C11H6N2O
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|---|---|
| Molecular Weight |
182.17814
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| Exact Mass |
182.048
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| CAS # |
54078-29-4
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| PubChem CID |
725961
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| Appearance |
Light yellow to yellow solid powder
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| Density |
1.4±0.1 g/cm3
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| Boiling Point |
396.3±17.0 °C at 760 mmHg
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| Melting Point |
229-233ºC
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| Flash Point |
196.1±27.4 °C
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| Vapour Pressure |
0.0±0.9 mmHg at 25°C
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| Index of Refraction |
1.689
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| LogP |
0.98
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
3
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| Rotatable Bond Count |
0
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| Heavy Atom Count |
14
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| Complexity |
230
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| Defined Atom Stereocenter Count |
0
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| InChi Key |
FOSUVSBKUIWVKI-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C11H6N2O/c14-11-9-7(3-1-5-12-9)8-4-2-6-13-10(8)11/h1-6H
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| Chemical Name |
6,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-8-one
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO : ~33.33 mg/mL (~182.95 mM)
H2O : ~0.67 mg/mL (~3.68 mM) |
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (13.72 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (13.72 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. View More
Solubility in Formulation 3: 2 mg/mL (10.98 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with ultrasonication (<60°C). |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 5.4891 mL | 27.4454 mL | 54.8908 mL | |
| 5 mM | 1.0978 mL | 5.4891 mL | 10.9782 mL | |
| 10 mM | 0.5489 mL | 2.7445 mL | 5.4891 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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