| Size | Price | Stock | Qty |
|---|---|---|---|
| 250mg |
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| 500mg |
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| Other Sizes |
| Targets |
Not well characterized; potential targets include olfactory receptors, inflammatory pathways, and microbial targets.
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|---|---|
| ln Vitro |
In vitro, Cedryl acetate has been reported to exhibit anti-inflammatory and antimicrobial activities. It may inhibit inflammatory cytokine production and microbial growth. Quantitative bioactivity data (IC50 values) is not detailed in publicly available sources.
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| ln Vivo |
In vivo, Cedryl acetate has been studied for its sedative and anti-inflammatory effects in animal models. It may have potential in aromatherapy and topical applications. Detailed dose-response and pharmacokinetic data are limited.
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| Enzyme Assay |
No specific cell-free assay protocol is detailed for Cedryl acetate. For sesquiterpenes, typical cell-free assays include antioxidant assays (DPPH, ABTS), enzyme inhibition assays (e.g., COX, LOX), and antimicrobial susceptibility tests.
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| Cell Assay |
Cellular activity is assessed in inflammatory cells (e.g., macrophages) or microbial cultures. Cells are treated with Cedryl acetate, and endpoints include cytokine production (ELISA), microbial growth inhibition (MIC determination), and cell viability.
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| Animal Protocol |
In vivo efficacy is evaluated in rodent models of inflammation or anxiety. Cedryl acetate is administered via inhalation or oral gavage. Endpoints include inflammatory biomarker analysis, behavioral tests, and histopathology.
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| ADME/Pharmacokinetics |
Molecular weight: 264.40; molecular formula: C17H28O2. Boiling point: 292°C. Density: 0.984-0.991 g/mL. Solubility: insoluble in water, soluble in ethanol and oils.
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| Toxicity/Toxicokinetics |
No detailed toxicity data is publicly available. As a natural fragrance compound, it is generally considered to have low toxicity.
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| References | |
| Additional Infomation |
Cedrol acetate is a cedrolane sesquiterpene compound. It has been reported that cedrol acetate is found in Artemisia annua, Artemisia argyi, and Japanese chamomile, but relevant data are still unclear.
Cedryl acetate is a fragrance ingredient and research compound, not approved as a drug. It is used in perfumery, cosmetics, and aromatherapy. No clinical trials have been reported for therapeutic use. Its potential applications include anti-inflammatory and sedative agents. |
| Molecular Formula |
C17H28O2
|
|---|---|
| Molecular Weight |
264.40302
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| Exact Mass |
264.208
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| CAS # |
77-54-3
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| PubChem CID |
13918856
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| Appearance |
White to off-white solid powder
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| Density |
1.0±0.1 g/cm3
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| Boiling Point |
291.7±8.0 °C at 760 mmHg
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| Melting Point |
44-46 °C
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| Flash Point |
137.0±6.0 °C
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| Vapour Pressure |
0.0±0.6 mmHg at 25°C
|
| Index of Refraction |
1.503
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| LogP |
5.67
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
2
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| Rotatable Bond Count |
2
|
| Heavy Atom Count |
19
|
| Complexity |
414
|
| Defined Atom Stereocenter Count |
5
|
| SMILES |
C[C@@H]1CC[C@@H]2[C@]13CC[C@@]([C@H](C3)C2(C)C)(C)OC(=O)C
|
| InChi Key |
HQKQRXZEXPXXIG-DTWJZALFSA-N
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| InChi Code |
InChI=1S/C17H28O2/c1-11-6-7-13-15(3,4)14-10-17(11,13)9-8-16(14,5)19-12(2)18/h11,13-14H,6-10H2,1-5H3/t11-,13+,14-,16-,17+/m1/s1
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| Chemical Name |
[(1S,2R,5S,7R,8R)-2,6,6,8-tetramethyl-8-tricyclo[5.3.1.01,5]undecanyl] acetate
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO : ~50 mg/mL (~189.11 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (9.46 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (9.46 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. View More
Solubility in Formulation 3: ≥ 2.5 mg/mL (9.46 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.7821 mL | 18.9107 mL | 37.8215 mL | |
| 5 mM | 0.7564 mL | 3.7821 mL | 7.5643 mL | |
| 10 mM | 0.3782 mL | 1.8911 mL | 3.7821 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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