Size | Price | Stock | Qty |
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500mg |
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1g |
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5g |
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10g |
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Other Sizes |
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Purity: ≥98%
Carbamazepine (formerly also known as CBZ, NSC-169864, Carbatrol; Tegretol, Epitol), an approved anticonvulsant drug, is a potent sodium channel blocker with IC50 of 131 μM in rat brain synaptosomes. Carbamazepine is a medication used primarily in the treatment of epilepsy and neuropathic pain. For seizures it works as well as phenytoin and valproate. It is not effective for absence seizures or myoclonic seizures. It may be used in schizophrenia along with other medications and as a second line agent in bipolar disorder.
ln Vitro |
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ln Vivo |
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Animal Protocol |
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References |
Mol Pharmacol.1982 Nov;22(3):627-35;Epilepsy Res.1997 Sep;28(2):143-53.
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Molecular Formula |
C15H12N2O
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Molecular Weight |
236.27
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CAS # |
298-46-4
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Related CAS # |
Carbamazepine-d10;132183-78-9;Carbamazepine-d2;1189902-21-3;Carbamazepine-d8;1538624-35-9;Carbamazepine-(Ph)d8
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SMILES |
O=C(C1=CC2=CC=CC=C2NC3=CC=CC=C13)N
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InChi Key |
RYLOOVOCHDAWIL-UHFFFAOYSA-N
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InChi Code |
InChI=1S/C15H12N2O/c16-15(18)12-9-10-5-1-3-7-13(10)17-14-8-4-2-6-11(12)14/h1-9,17H,(H2,16,18)
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Chemical Name |
benzo[b][1]benzazepine-11-carboxamideInChi Key: RYLOOVOCHDAWIL-UHFFFAOYSA-N
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Synonyms |
NSC 169864; Carbamazepine, NSC 69864; NSC-169864;Tegretol, Epitol
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Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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Solubility (In Vitro) |
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Solubility (In Vivo) |
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Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
1 mM | 4.2324 mL | 21.1622 mL | 42.3245 mL | |
5 mM | 0.8465 mL | 4.2324 mL | 8.4649 mL | |
10 mM | 0.4232 mL | 2.1162 mL | 4.2324 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration: mg/mL;
Method for preparing DMSO stock solution: mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation::Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.