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α-Lactose

Alias: αLactose; α Lactose
Cat No.:V38719 Purity: ≥98%
Alpha-Lactose is the main sugar in milk.
α-Lactose
α-Lactose Chemical Structure CAS No.: 14641-93-1
Product category: New2
This product is for research use only, not for human use. We do not sell to patients.
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Product Description
Alpha-Lactose is the main sugar in milk. Lactose exists in two isomers, alpha and beta. The alpha form usually crystallizes as the monohydrate.
Biological Activity I Assay Protocols (From Reference)
ln Vitro
Because it is present in large quantities in both human and domestic animal milk, lactose is a highly significant sugar. When lactose is fermented to generate dairy products like kefir and yogurt, it becomes a valuable asset, a necessary nutrient, and the main substrate [3].
References

[1]. Lactose crystallization: determination of α-lactose monohydrate in spray-dried dairy products. (2002).

[2]. Lactose.

[3]. Lactose: The Milk Sugar From a Biotechnological Perspective. Crit Rev Food Sci Nutr. 2004;44(7-8):553-7.

Additional Infomation
Alpha-lactose is the alpha-anomer of lactose.
alpha-Lactose is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
alpha-Lactose has been reported in Penicillium chrysogenum with data available.
A disaccharide of GLUCOSE and GALACTOSE in human and cow milk. It is used in pharmacy for tablets, in medicine as a nutrient, and in industry.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Physicochemical Properties
Molecular Formula
C₁₂H₂₂O₁₁
Molecular Weight
342.30
Exact Mass
342.116
CAS #
14641-93-1
PubChem CID
84571
Appearance
White to light yellow solid powder
Density
1.76 g/cm3
Boiling Point
667.9ºC at 760 mmHg
Melting Point
201-202ºC
Flash Point
357.8ºC
Vapour Pressure
1.08E-20mmHg at 25°C
Index of Refraction
52.5 ° (C=10, H2O)
LogP
-4.7
Hydrogen Bond Donor Count
8
Hydrogen Bond Acceptor Count
11
Rotatable Bond Count
4
Heavy Atom Count
23
Complexity
382
Defined Atom Stereocenter Count
10
SMILES
C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O)CO)O)O)O)O
InChi Key
GUBGYTABKSRVRQ-XLOQQCSPSA-N
InChi Code
InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+/m1/s1
Chemical Name
(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
Synonyms
αLactose; α Lactose
HS Tariff Code
2934.99.9001
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.
Shipping Condition
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
Solubility Data
Solubility (In Vitro)
H2O : ~62.5 mg/mL (~182.59 mM)
Solubility (In Vivo)
Solubility in Formulation 1: 25 mg/mL (73.04 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication (<60°C).

 (Please use freshly prepared in vivo formulations for optimal results.)
Preparing Stock Solutions 1 mg 5 mg 10 mg
1 mM 2.9214 mL 14.6071 mL 29.2141 mL
5 mM 0.5843 mL 2.9214 mL 5.8428 mL
10 mM 0.2921 mL 1.4607 mL 2.9214 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.

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What is the mass of compound required to make a 10 mM stock solution in 5 ml of DMSO given that the molecular weight of the compound is 350.26 g/mol?
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Dilution Calculator allows you to calculate how to dilute a stock solution of known concentrations. For example, you may Enter C1, C2 & V2 to calculate V1, as detailed below:

What volume of a given 10 mM stock solution is required to make 25 ml of a 25 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=25 μM, V2=25 ml and V1 is the unknown:
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g/mol

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Note: Chemical formula is case sensitive: C12H18N3O4  c12h18n3o4
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Definitions of molecular mass, molecular weight, molar mass and molar weight:
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In vivo Formulation Calculator (Clear solution)
Step 1: Enter information below (Recommended: An additional animal to make allowance for loss during the experiment)
Step 2: Enter in vivo formulation (This is only a calculator, not the exact formulation for a specific product. Please contact us first if there is no in vivo formulation in the solubility section.)
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Calculation results

Working concentration mg/mL;

Method for preparing DMSO stock solution mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation:Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
             (2) Be sure to add the solvent(s) in order.

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