| Size | Price | |
|---|---|---|
| Other Sizes |
| ln Vitro |
Because it is present in large quantities in both human and domestic animal milk, lactose is a highly significant sugar. When lactose is fermented to generate dairy products like kefir and yogurt, it becomes a valuable asset, a necessary nutrient, and the main substrate [3].
|
|---|---|
| References | |
| Additional Infomation |
Alpha-lactose is the α-isomer of lactose. Alpha-lactose is a metabolite found or produced in Escherichia coli (strains K12 and MG1655). It has been reported that α-lactose is also present in Penicillium chrysogenum, but the relevant data is unclear. Both human and cow's milk contain a disaccharide composed of glucose and galactose. It is used in pharmaceuticals for tablets, as a nutrient in medicine, and also has industrial applications.
|
| Molecular Formula |
C₁₂H₂₂O₁₁
|
|---|---|
| Molecular Weight |
342.30
|
| Exact Mass |
342.116
|
| CAS # |
14641-93-1
|
| PubChem CID |
84571
|
| Appearance |
White to light yellow solid powder
|
| Density |
1.76 g/cm3
|
| Boiling Point |
667.9ºC at 760 mmHg
|
| Melting Point |
201-202ºC
|
| Flash Point |
357.8ºC
|
| Vapour Pressure |
1.08E-20mmHg at 25°C
|
| Index of Refraction |
52.5 ° (C=10, H2O)
|
| LogP |
-4.7
|
| Hydrogen Bond Donor Count |
8
|
| Hydrogen Bond Acceptor Count |
11
|
| Rotatable Bond Count |
4
|
| Heavy Atom Count |
23
|
| Complexity |
382
|
| Defined Atom Stereocenter Count |
10
|
| SMILES |
C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O)CO)O)O)O)O
|
| InChi Key |
GUBGYTABKSRVRQ-XLOQQCSPSA-N
|
| InChi Code |
InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+/m1/s1
|
| Chemical Name |
(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
|
| Synonyms |
αLactose; α Lactose
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
H2O : ~62.5 mg/mL (~182.59 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 25 mg/mL (73.04 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication (<60°C).
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.9214 mL | 14.6071 mL | 29.2141 mL | |
| 5 mM | 0.5843 mL | 2.9214 mL | 5.8428 mL | |
| 10 mM | 0.2921 mL | 1.4607 mL | 2.9214 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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