| Size | Price | Stock | Qty |
|---|---|---|---|
| 100mg |
|
||
| Other Sizes |
| Targets |
Human Endogenous Metabolite
|
|---|---|
| References | |
| Additional Infomation |
CTP stands for pyrimidine ribonucleoside 5'-triphosphate and cytidine 5'-phosphate. It is a metabolite in both E. coli and mice. It is the conjugate acid of CTP(4-) and CTP(3-). Cytidine triphosphate is a metabolite found or produced in E. coli (K12 strain, MG1655 strain). It has been reported to be detected in Homo sapiens, Apis cerana, and Caenorhabditis elegans, with relevant data available. Cytidine triphosphate is a cytosine-derived nucleotide composed of three phosphate groups esterified onto a deoxyribose glycosyl group. Nucleotide metabolism is upregulated in cancer cells; therefore, this nucleotide can be used as a biomarker for detecting the presence of cancer cells. Cytidine triphosphate is a metabolite found or produced in Saccharomyces cerevisiae. Cytidine 5'-(tetrahydrotriphosphate). A cytosine nucleotide whose glycosyl moiety is esterified with three phosphate groups.
|
| Molecular Formula |
C9H16N3O14P3
|
|---|---|
| Molecular Weight |
483.16
|
| Exact Mass |
482.984
|
| CAS # |
65-47-4
|
| Related CAS # |
Cytidine-5'-triphosphate disodium;36051-68-0;Cytidine-5′-triphosphate-d14 disodium
|
| PubChem CID |
6176
|
| Appearance |
White to off-white solid powder
|
| Density |
2.5±0.1 g/cm3
|
| Boiling Point |
849.2±75.0 °C at 760 mmHg
|
| Melting Point |
215 - 218 °C
|
| Flash Point |
467.4±37.1 °C
|
| Vapour Pressure |
0.0±0.6 mmHg at 25°C
|
| Index of Refraction |
1.801
|
| LogP |
-5.52
|
| Hydrogen Bond Donor Count |
7
|
| Hydrogen Bond Acceptor Count |
14
|
| Rotatable Bond Count |
8
|
| Heavy Atom Count |
29
|
| Complexity |
855
|
| Defined Atom Stereocenter Count |
4
|
| SMILES |
C1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O
|
| InChi Key |
PCDQPRRSZKQHHS-XVFCMESISA-N
|
| InChi Code |
InChI=1S/C9H16N3O14P3/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
|
| Chemical Name |
[[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
H2O : 83.33 mg/mL (172.47 mM)
DMSO : < 1 mg/mL |
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 100 mg/mL (206.97 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.0697 mL | 10.3485 mL | 20.6971 mL | |
| 5 mM | 0.4139 mL | 2.0697 mL | 4.1394 mL | |
| 10 mM | 0.2070 mL | 1.0349 mL | 2.0697 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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