| Size | Price | Stock | Qty |
|---|---|---|---|
| 500mg |
|
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| Other Sizes |
| Targets |
No specific molecular target. It is a metabolite and chemical building block.
|
|---|---|
| ln Vitro |
8-Aminooctanoic acid is a substrate or reactant in various chemical and enzymatic reactions. For example, it is involved in the preparation of lactams using enzyme-catalyzed aminolysis. Its activity is defined by its role as a chemical precursor, not by a specific biological activity.
|
| ln Vivo |
As a natural human metabolite, 8-aminooctanoic acid is expected to participate in normal metabolic processes. However, specific pharmacological in vivo activity is not documented; its primary use is as a research chemical.
|
| Enzyme Assay |
In vitro experiments typically use 8-aminooctanoic acid as a reagent. For example, it can be used in enzymatic assays to study the kinetics of aminolysis or as a standard in analytical chemistry. Its purity and solubility (soluble in water) are key parameters in these assays.
|
| Cell Assay |
In cellular assays, it may be used as a supplement in cell culture media to study amino acid transport or metabolism. It can also be used in studies of peptide-based material synthesis or as a linker in bioconjugation chemistry.
|
| Animal Protocol |
In vivo animal experiments are not typical for this compound as a research tool. However, as a metabolite, its levels in biological fluids (e.g., urine) could be monitored in metabolic studies.
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| ADME/Pharmacokinetics |
As a small, polar molecule, it is expected to have good aqueous solubility. Its pharmacokinetics would be similar to other amino acids and fatty acids, involving absorption, distribution, and metabolism via normal physiological pathways. It is not administered as a drug.
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| Toxicity/Toxicokinetics |
8-Aminooctanoic acid is generally considered safe as an endogenous metabolite. However, as with all research chemicals, standard laboratory safety precautions should be observed. It is not intended for human therapeutic use.
|
| References | |
| Additional Infomation |
8-Aminooctanoic acid (8-aminooctanoic acid) is an omega-amino fatty acid, a derivative of octanoic acid at the 8-amino group. It plays a role in human metabolism. It is a medium-chain fatty acid and an omega-amino fatty acid.
8-Aminooctanoic acid is a biochemical and chemical research tool used in peptide synthesis, protein engineering, and studies of molecular transport. It is not a drug. |
| Molecular Formula |
C₈H₁₇NO₂
|
|---|---|
| Molecular Weight |
159.23
|
| Exact Mass |
159.125
|
| CAS # |
1002-57-9
|
| Related CAS # |
27306-03-2
|
| PubChem CID |
66085
|
| Appearance |
White to light yellow solid powder
|
| Density |
1.0±0.1 g/cm3
|
| Boiling Point |
286.0±23.0 °C at 760 mmHg
|
| Melting Point |
194 °C (dec.)(lit.)
|
| Flash Point |
126.8±22.6 °C
|
| Vapour Pressure |
0.0±1.3 mmHg at 25°C
|
| Index of Refraction |
1.469
|
| LogP |
0.95
|
| Hydrogen Bond Donor Count |
2
|
| Hydrogen Bond Acceptor Count |
3
|
| Rotatable Bond Count |
7
|
| Heavy Atom Count |
11
|
| Complexity |
104
|
| Defined Atom Stereocenter Count |
0
|
| InChi Key |
UQXNEWQGGVUVQA-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C8H17NO2/c9-7-5-3-1-2-4-6-8(10)11/h1-7,9H2,(H,10,11)
|
| Chemical Name |
8-aminooctanoic acid
|
| Synonyms |
8Aminooctanoic acid; 8 Aminooctanoic acid
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
H2O : ~100 mg/mL (~628.02 mM)
DMSO :< 1 mg/mL |
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 100 mg/mL (628.02 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 6.2802 mL | 31.4011 mL | 62.8022 mL | |
| 5 mM | 1.2560 mL | 6.2802 mL | 12.5604 mL | |
| 10 mM | 0.6280 mL | 3.1401 mL | 6.2802 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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