| Size | Price | Stock | Qty |
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| 1mg |
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| 5mg |
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| 10mg |
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| 100mg | |||
| Other Sizes |
| Targets |
7-Prenyloxycoumarin does not have a well-defined specific biological target. As a secondary metabolite, it is known for its diverse biological properties, including antimicrobial, anti-inflammatory, and anticancer potential. Its mechanism of action is likely related to its ability to modulate various cellular pathways.
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|---|---|
| ln Vitro |
In vitro studies demonstrate that 7-Prenyloxycoumarin exhibits antimicrobial, anti-inflammatory, and anticancer activities. It is a secondary metabolite and is used in research to study its biological properties and potential therapeutic applications.
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| ln Vivo |
In vivo activity of 7-Prenyloxycoumarin has not been extensively characterized. As a natural product with diverse biological properties, it has potential for pharmaceutical and biochemical research. However, detailed in vivo efficacy data are not available in the provided literature.
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| Enzyme Assay |
In vitro assays for 7-Prenyloxycoumarin are not well-defined. As a compound with antimicrobial, anti-inflammatory, and anticancer activities, its effects could be assessed using standard assays such as broth microdilution for antimicrobial activity, cytokine ELISA for anti-inflammatory activity, and MTT assays for anticancer activity.
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| Cell Assay |
Cellular assays for 7-Prenyloxycoumarin are not well-defined. Depending on the biological activity being studied, it could be tested in various cell lines. For anticancer activity, cancer cell lines would be treated with the compound and cell viability measured.
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| Animal Protocol |
In vivo animal studies for 7-Prenyloxycoumarin are limited. For studying its anti-inflammatory effects, animal models of inflammation could be used. For anticancer effects, xenograft models could be employed.
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| ADME/Pharmacokinetics |
The pharmacokinetic properties of 7-Prenyloxycoumarin are characteristic of a small molecule. It has a molecular weight of 230.26 and a molecular formula of C14H14O3. It is a secondary metabolite and is typically stored at -20degC.
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| Toxicity/Toxicokinetics |
The toxicological data for 7-Prenyloxycoumarin are limited. As a natural product, it is generally considered to have a favorable safety profile. However, it is intended for research purposes only and is not for human therapeutic use. Standard safety precautions should be followed.
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| References | |
| Additional Infomation |
7-Isopentyloxycoumarin has been reported in Heracleum dissectum, Melicope semecarpifolia, and other organisms with available data.
7-Prenyloxycoumarin is a naturally occurring coumarin derivative. It is a secondary metabolite of the endophytic fungus Annulohypoxylon ilanense and is also found in plants. It exhibits antimicrobial, anti-inflammatory, and anticancer potential and is used in pharmaceutical and biochemical research. |
| Molecular Formula |
C14H14O3
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|---|---|
| Molecular Weight |
230.2592
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| Exact Mass |
230.094
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| CAS # |
10387-50-5
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| PubChem CID |
320362
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| Appearance |
White to off-white solid powder
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| Density |
1.148g/cm3
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| Boiling Point |
390.9ºC at 760mmHg
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| Flash Point |
164.9ºC
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| Vapour Pressure |
2.56E-06mmHg at 25°C
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| Index of Refraction |
1.56
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| LogP |
3.138
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
3
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| Rotatable Bond Count |
3
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| Heavy Atom Count |
17
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| Complexity |
339
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| Defined Atom Stereocenter Count |
0
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| InChi Key |
SMHJTSOVVRGDEO-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C14H14O3/c1-10(2)7-8-16-12-5-3-11-4-6-14(15)17-13(11)9-12/h3-7,9H,8H2,1-2H3
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| Chemical Name |
7-(3-methylbut-2-enoxy)chromen-2-one
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO : ~100 mg/mL (~434.29 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (10.86 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (10.86 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. View More
Solubility in Formulation 3: ≥ 2.5 mg/mL (10.86 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.3429 mL | 21.7146 mL | 43.4292 mL | |
| 5 mM | 0.8686 mL | 4.3429 mL | 8.6858 mL | |
| 10 mM | 0.4343 mL | 2.1715 mL | 4.3429 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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