| Size | Price | Stock | Qty |
|---|---|---|---|
| 10g |
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| Other Sizes |
| Targets |
7-Octyn-1-ol does not have a specific biological target as a drug; it is a chemical reagent. Its terminal alkyne group makes it useful for click chemistry reactions, such as the copper-catalyzed azide-alkyne cycloaddition (CuAAC). It is used as a precursor for the synthesis of 7-octynoic acid and other bioactive molecules.
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|---|---|
| ln Vitro |
7-Octyn-1-ol is not evaluated for biological activity as a drug; it is a chemical reagent. Its utility is assessed by its reactivity and use as a building block in organic synthesis and click chemistry.
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| ln Vivo |
7-Octyn-1-ol is not evaluated for in vivo biological activity as a drug; it is a chemical reagent. It is not administered as a therapeutic agent. The compound is used in the synthesis of bioactive molecules that may subsequently be tested in animal models.
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| Enzyme Assay |
There are no specific in vitro enzyme or receptor binding assays for 7-Octyn-1-ol as a drug target. As a chemical reagent, it is characterized by its chemical properties, including molecular formula (C8H14O) and molecular weight (126.20).
|
| Cell Assay |
There are no specific in vitro cellular assays for 7-Octyn-1-ol as a pharmacologically active compound. As a chemical building block, it is not typically tested in cell culture. The compound is used to synthesize bioactive molecules that are subsequently tested in cellular assays.
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| Animal Protocol |
There are no specific in vivo animal studies for 7-Octyn-1-ol as a pharmacologically active compound. As a chemical reagent, it is not administered to animals. The compound is used to synthesize compounds that may subsequently be tested in animal models.
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| ADME/Pharmacokinetics |
Pharmacokinetic properties of 7-Octyn-1-ol are not applicable, as it is a chemical reagent rather than a drug. The compound is not intended for administration as a therapeutic agent.
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| Toxicity/Toxicokinetics |
The toxicity profile of 7-Octyn-1-ol is not extensively reported. As a chemical reagent, it should be handled with care in a laboratory setting. The compound is not intended for human therapeutic use.
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| References | |
| Additional Infomation |
7-Octyn-1-ol (CAS 871-91-0) is a terminal alkyne alcohol with a molecular formula of C8H14O and a molecular weight of 126.20. It is the precursor to 7-octynoic acid and is a reagent for click chemistry. The compound is used as a building block in organic synthesis and is available for research purposes only.
|
| Molecular Formula |
C8H14O
|
|---|---|
| Molecular Weight |
126.1962
|
| Exact Mass |
126.104
|
| CAS # |
871-91-0
|
| PubChem CID |
70100
|
| Appearance |
Colorless to light yellow liquid
|
| Density |
0.9±0.1 g/cm3
|
| Boiling Point |
191.5±23.0 °C at 760 mmHg
|
| Flash Point |
116.3±14.9 °C
|
| Vapour Pressure |
0.1±0.8 mmHg at 25°C
|
| Index of Refraction |
1.455
|
| LogP |
1.65
|
| Hydrogen Bond Donor Count |
1
|
| Hydrogen Bond Acceptor Count |
1
|
| Rotatable Bond Count |
5
|
| Heavy Atom Count |
9
|
| Complexity |
88
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
C#CCCCCCCO
|
| InChi Key |
ATCNYMVVGBLQMQ-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C8H14O/c1-2-3-4-5-6-7-8-9/h1,9H,3-8H2
|
| Chemical Name |
oct-7-yn-1-ol
|
| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
DMSO : ~100 mg/mL (~792.39 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (19.81 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (19.81 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. View More
Solubility in Formulation 3: ≥ 2.5 mg/mL (19.81 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 7.9239 mL | 39.6197 mL | 79.2393 mL | |
| 5 mM | 1.5848 mL | 7.9239 mL | 15.8479 mL | |
| 10 mM | 0.7924 mL | 3.9620 mL | 7.9239 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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