| Size | Price | Stock | Qty |
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| 50mg |
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| 100mg |
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| 250mg |
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| 500mg |
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| 1g |
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| Other Sizes |
| Targets |
3,6-Dichlorotrimellitic acid does not have a defined pharmacological target, as it is a chemical intermediate rather than a therapeutic agent. The compound is not designed to interact with biological receptors, enzymes, or ion channels. Its primary utility lies in organic synthesis, where it serves as a precursor for the preparation of fluorescent dyes and labeling reagents. Any biological activity associated with the compound would be incidental and related to its chemical reactivity as a carboxylic acid and chlorinated aromatic compound, rather than specific target engagement.
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| ln Vitro |
In vitro activity of 3,6-dichlorotrimellitic acid has not been characterized in pharmacological or biological assays, as the compound is not intended for use as a bioactive molecule. It is a chemical intermediate used in organic synthesis rather than a drug candidate. No cytotoxicity, enzyme inhibition, or receptor binding data are available for this compound. The compound's chemical reactivity, particularly its carboxylic acid groups, may allow it to participate in non-specific interactions with biological molecules, but these are not relevant to its intended applications as a synthetic precursor.
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| ln Vivo |
In vivo activity of 3,6-dichlorotrimellitic acid has not been characterized in animal models, as the compound is not intended for use as a therapeutic or bioactive agent. No animal studies have been conducted to evaluate its pharmacological effects, efficacy, or safety in vivo. The compound is a chemical intermediate used exclusively in laboratory synthesis applications. Any in vivo exposure would be incidental and not relevant to its intended use. The compound is not administered to animals for research purposes.
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| Enzyme Assay |
In vitro enzyme/receptor binding assays are not applicable to 3,6-dichlorotrimellitic acid, as the compound is not a bioactive molecule designed to interact with biological targets. The compound is a chemical intermediate used in organic synthesis for the preparation of fluorescent dyes. No standard binding assays have been developed or performed for this compound. Any interaction with biological molecules would be non-specific and related to the compound's carboxylic acid groups or aromatic chlorine substituents, rather than targeted binding to a specific receptor or enzyme.
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| Cell Assay |
In vitro cell-based assays are not applicable to 3,6-dichlorotrimellitic acid, as the compound is not a bioactive molecule intended for cell-based studies. The compound is a chemical intermediate used in organic synthesis. No cytotoxicity, proliferation, or signaling assays have been performed with this compound in cell culture systems. The compound is not used in cell biology research applications. Any cell-based studies would be unrelated to its intended use as a synthetic precursor for fluorescent dyes.
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| Animal Protocol |
In vivo animal studies are not applicable to 3,6-dichlorotrimellitic acid, as the compound is not intended for use as a therapeutic or bioactive agent. No animal studies have been conducted to evaluate its pharmacokinetics, efficacy, or toxicology. The compound is a chemical intermediate used exclusively in laboratory synthesis. It is not administered to animals for research purposes. Any in vivo exposure would be incidental and not relevant to its intended applications as a precursor for fluorescent dyes.
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| ADME/Pharmacokinetics |
Pharmacokinetic (PK) properties of 3,6-dichlorotrimellitic acid have not been characterized, as the compound is not a therapeutic agent. No absorption, distribution, metabolism, or excretion studies have been conducted. The compound is a chemical intermediate used in organic synthesis, and its PK properties are not relevant to its intended applications. As a small polar molecule with multiple carboxylic acid groups, the compound would be expected to have low oral bioavailability and limited membrane permeability, but these properties have not been experimentally determined.
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| Toxicity/Toxicokinetics |
The toxicity profile of 3,6-dichlorotrimellitic acid has not been extensively characterized in preclinical studies, as the compound is not a therapeutic agent. As a chlorinated aromatic carboxylic acid, the compound may exhibit irritant properties and should be handled with appropriate safety precautions. No specific toxicology data, including acute toxicity, genotoxicity, or chronic toxicity studies, are available in the published literature. The compound is intended for research and synthesis applications only and is not approved for human use. Standard safety precautions for handling chlorinated aromatic compounds should be followed.
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| Additional Infomation |
3,6-Dichlorotrimellitic acid is a research-grade chemical intermediate primarily used as a precursor for the synthesis of dichlorinated fluorescein and rhodamine dyes, including TET and HEX. These dyes are widely used for labeling oligonucleotides and in DNA sequencing applications. The compound is not an approved therapeutic drug and has no clinical applications. It is supplied as a solid powder and should be stored in a cool, dry place. Synonyms include 3,6-dichlorobenzene-1,2,4-tricarboxylic acid and 2,5-dichloro-1,3,4-benzenetricarboxylic acid. The compound is for research use only and not for human or veterinary use.
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| Molecular Formula |
C9H4CL2O6
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|---|---|
| Molecular Weight |
279.0305
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| Exact Mass |
277.938
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| CAS # |
137071-78-4
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| PubChem CID |
15923461
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| Appearance |
White to off-white solid powder
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| LogP |
2.088
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| Hydrogen Bond Donor Count |
3
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| Hydrogen Bond Acceptor Count |
6
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| Rotatable Bond Count |
3
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| Heavy Atom Count |
17
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| Complexity |
357
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| Defined Atom Stereocenter Count |
0
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| InChi Key |
WFLALXNBVTWGKP-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C9H4Cl2O6/c10-3-1-2(7(12)13)6(11)5(9(16)17)4(3)8(14)15/h1H,(H,12,13)(H,14,15)(H,16,17)
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| Chemical Name |
3,6-dichlorobenzene-1,2,4-tricarboxylic acid
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO : ~250 mg/mL (~895.96 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.08 mg/mL (7.45 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 20.8 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.08 mg/mL (7.45 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 20.8 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.5838 mL | 17.9192 mL | 35.8384 mL | |
| 5 mM | 0.7168 mL | 3.5838 mL | 7.1677 mL | |
| 10 mM | 0.3584 mL | 1.7919 mL | 3.5838 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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