| Size | Price | |
|---|---|---|
| Other Sizes |
| ln Vitro |
One common organic acid found in honey and meals fermented by lactic acid bacteria is called DL-3-Phenyllactic Acid (PLA). Many different microorganisms, particularly lactic acid bacteria, are capable of producing it. With a wide range of effective antibacterial action against both bacteria and fungi, DL-3-phenyllactic acid has shown to be an excellent antimicrobial chemical. Furthermore, DL-3-phenyllactic acid has the potential to serve as a feed additive in substitution of antibiotics in animal feed [1].
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|---|---|
| References | |
| Additional Infomation |
3-phenyllactic acid is a 2-hydroxy monocarboxylic acid that is lactic acid in which one of the methyl hydrogens is substituted by a phenyl group. It has a role as a human metabolite. It is functionally related to a rac-lactic acid. It is a conjugate acid of a 3-phenyllactate.
DL-3-Phenyllactic acid has been reported in Rosa taiwanensis, Secale cereale, and other organisms with data available. |
| Molecular Formula |
C9H10O3
|
|---|---|
| Molecular Weight |
166.17
|
| Exact Mass |
166.062
|
| CAS # |
828-01-3
|
| Related CAS # |
57618-25-4 (mono-Na salt);57618-26-5 (Ca salt)
|
| PubChem CID |
3848
|
| Appearance |
White to off-white solid powder
|
| Density |
1.3±0.1 g/cm3
|
| Boiling Point |
331.6±22.0 °C at 760 mmHg
|
| Melting Point |
95-98 °C
|
| Flash Point |
168.5±18.8 °C
|
| Vapour Pressure |
0.0±0.8 mmHg at 25°C
|
| Index of Refraction |
1.577
|
| LogP |
1.05
|
| Hydrogen Bond Donor Count |
2
|
| Hydrogen Bond Acceptor Count |
3
|
| Rotatable Bond Count |
3
|
| Heavy Atom Count |
12
|
| Complexity |
150
|
| Defined Atom Stereocenter Count |
0
|
| InChi Key |
VOXXWSYKYCBWHO-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C9H10O3/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8,10H,6H2,(H,11,12)
|
| Chemical Name |
Benzenepropanoic acid, alpha-hydroxy-
|
| Synonyms |
3Phenyllactic acid3 Phenyllactic acid 3-Phenyllactic acid NSC-2627 NSC2627NSC 2627Ba 2653 Ba-2653 Ba2653
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
DMSO : ~125 mg/mL (~752.20 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.08 mg/mL (12.52 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 20.8 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.08 mg/mL (12.52 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 20.8 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. View More
Solubility in Formulation 3: ≥ 2.08 mg/mL (12.52 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 6.0179 mL | 30.0897 mL | 60.1793 mL | |
| 5 mM | 1.2036 mL | 6.0179 mL | 12.0359 mL | |
| 10 mM | 0.6018 mL | 3.0090 mL | 6.0179 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
| NCT Number | Recruitment | interventions | Conditions | Sponsor/Collaborators | Start Date | Phases |
| NCT05887544 | COMPLETED | Other: Exposure: Plant-based diet pattern Other: Intervention: Fermented dairy products Other: Exposure: individual foods and food groups |
Diabetes Mellitus, Type 2 | University of Copenhagen | 2023-06-01 | |
| NCT05067465 | COMPLETED | Dietary Supplement: Selected food groups | Healthy Lifestyle | University of Jena | 2021-10-14 | Not Applicable |
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