| Size | Price | Stock | Qty |
|---|---|---|---|
| 5g |
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| 10g |
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| Other Sizes |
| Targets |
3-Methoxyphenylacetic acid does not have a well-defined pharmacological target. It is used as a chemical intermediate and research compound rather than a therapeutic agent. Its biological activities, if any, are not extensively characterized in the available literature.
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|---|---|
| ln Vitro |
Specific in vitro biological activities have not been extensively reported. The compound is primarily used as a building block in organic synthesis and as a research chemical. Its potential biological effects would depend on the specific context of its use.
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| ln Vivo |
In vivo activity has not been reported. The compound is not a drug and is not intended for therapeutic use. It is used exclusively for research and chemical synthesis purposes.
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| Enzyme Assay |
Receptor binding or enzyme inhibition assays are not standard for this compound. Characterization typically involves HPLC, GC, NMR, and mass spectrometry. Purity is assessed by GC (≥97.0%) and neutralization titration (≥98.0%).
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| Cell Assay |
Cell-based assays are not typically performed for 3-Methoxyphenylacetic acid as it is not a pharmacologically active compound. Its use in cell culture would be limited to applications as a chemical intermediate or reference standard.
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| Animal Protocol |
In vivo animal studies are not conducted for this compound as it is not a therapeutic agent. It is used exclusively in laboratory settings for chemical synthesis and analytical purposes.
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| ADME/Pharmacokinetics |
3-Methoxyphenylacetic acid has a melting point of 65-73°C and a boiling point of approximately 306°C. It is slightly soluble in water and soluble in chloroform and ethyl acetate. Storage: below +30°C. Density: 1.1708 g/cm³.
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| Toxicity/Toxicokinetics |
3-Methoxyphenylacetic acid is not classified as a hazardous compound under normal handling conditions. Standard laboratory safety precautions should be followed, including the use of appropriate personal protective equipment and proper ventilation.
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| References | |
| Additional Infomation |
3-Methoxyphenylacetic acid is a monocarboxylic acid. It has been reported that 3-methoxyphenylacetic acid is present in Malabar spinach and Rhizoctonia solani, and relevant data are available for reference.
3-Methoxyphenylacetic acid is a research chemical used as a building block in organic synthesis. It is not a pharmaceutical drug and has no approved clinical indications. The compound is available from multiple chemical suppliers for research purposes. |
| Molecular Formula |
C₉H₁₀O₃
|
|---|---|
| Molecular Weight |
166.17
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| Exact Mass |
166.062
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| CAS # |
1798-09-0
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| PubChem CID |
15719
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| Appearance |
White to off-white solid powder
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| Density |
1.2±0.1 g/cm3
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| Boiling Point |
305.5±17.0 °C at 760 mmHg
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| Melting Point |
65-69 °C(lit.)
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| Flash Point |
124.1±14.4 °C
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| Vapour Pressure |
0.0±0.7 mmHg at 25°C
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| Index of Refraction |
1.538
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| LogP |
1.42
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| Hydrogen Bond Donor Count |
1
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| Hydrogen Bond Acceptor Count |
3
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| Rotatable Bond Count |
3
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| Heavy Atom Count |
12
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| Complexity |
156
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| Defined Atom Stereocenter Count |
0
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| InChi Key |
LEGPZHPSIPPYIO-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C9H10O3/c1-12-8-4-2-3-7(5-8)6-9(10)11/h2-5H,6H2,1H3,(H,10,11)
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| Chemical Name |
2-(3-methoxyphenyl)acetic acid
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| Synonyms |
3Methoxyphenylacetic acid; 3 Methoxyphenylacetic acid
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO : ~100 mg/mL (~601.79 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (15.04 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (15.04 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. View More
Solubility in Formulation 3: ≥ 2.5 mg/mL (15.04 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 6.0179 mL | 30.0897 mL | 60.1793 mL | |
| 5 mM | 1.2036 mL | 6.0179 mL | 12.0359 mL | |
| 10 mM | 0.6018 mL | 3.0090 mL | 6.0179 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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