| Size | Price | Stock | Qty |
|---|---|---|---|
| 500mg |
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| Other Sizes |
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| ln Vivo |
Twenty days following the induction of tendinitis, saline was administered to the contralateral limb and 3-acetone acetone fumarate (2:1) (BAPN-F) was used as an intralesional therapy. On day 150 of the trial, biopsies were taken, and they were analyzed grossly and histologically. Both ultrasonography and histological analysis revealed that the 3-acetone acetone fumarate (2:1) group had a better collagen fiber arrangement pattern in the repair area than the other group. According to the current findings, controlled obesity plus fumarate 3-acetone-acetone (2:1) reduces scarring and increases collagen in tendon wounds [1].
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|---|---|
| References | |
| Additional Infomation |
Beta-aminopropionitrile hemifumarate is a fumarate salt prepared from beta-aminopropionitrile by reaction of one molecule of fumaric acid for every two molecules of beta-aminopropionitrile. It has a role as an antineoplastic agent, an antirheumatic drug, a collagen cross-linking inhibitor and a plant metabolite. It contains a beta-ammoniopropionitrile.
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| Molecular Formula |
C10H16N4O4
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|---|---|
| Molecular Weight |
256.2584
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| Exact Mass |
186.064
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| CAS # |
2079-89-2
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| Related CAS # |
1119-28-4 (Parent);110-17-8 (Parent);151-18-8 (Parent)
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| PubChem CID |
5462653
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| Appearance |
White to off-white solid powder
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| Boiling Point |
355.5ºC at 760 mmHg
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| Melting Point |
177 °C (dec.)(lit.)
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| Flash Point |
183ºC
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| Vapour Pressure |
5.19E-06mmHg at 25°C
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| LogP |
0.27
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| Hydrogen Bond Donor Count |
4
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| Hydrogen Bond Acceptor Count |
8
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| Rotatable Bond Count |
4
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| Heavy Atom Count |
18
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| Complexity |
168
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| Defined Atom Stereocenter Count |
0
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| SMILES |
C(CN)C#N.C(CN)C#N.C(=C/C(=O)O)\C(=O)O
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| InChi Key |
NYMXYZMHOZAPHQ-SEPHDYHBSA-N
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| InChi Code |
InChI=1S/C4H4O4.2C3H6N2/c5-3(6)1-2-4(7)8;2*4-2-1-3-5/h1-2H,(H,5,6)(H,7,8);2*1-2,4H2/b2-1+;;
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| Chemical Name |
3-aminopropanenitrile;(E)-but-2-enedioic acid
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
H2O : ~125 mg/mL (~487.79 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 100 mg/mL (390.23 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.9023 mL | 19.5114 mL | 39.0229 mL | |
| 5 mM | 0.7805 mL | 3.9023 mL | 7.8046 mL | |
| 10 mM | 0.3902 mL | 1.9511 mL | 3.9023 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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