| Size | Price | Stock | Qty |
|---|---|---|---|
| 200g |
|
||
| Other Sizes |
|
Purity: ≥98%
2,2′-Azobis(2-methylpropionitrile), also named as AIBN, 2,2′-Azobis(2-methylpropionitrile), is a free radical initiator. It is the most common oil-soluble azo polymerization initiator, and is used for polymerization of versatile polymers. It can also be used for: 1) preparation of Polystyrene by soap free lotion polymerization; 2) preparation of molecularly imprinted polymers (MIPs) using 1-vinylimidazole. MIP can be used for quantitative detection of acid purple 19 dye in river water samples.
| Targets |
free radical initiator; catalyst; vinyl polymerizations; blowing agent for plastics.
|
|---|---|
| ln Vitro |
Used as blowing agent (elastomers and plastics), catalyst (vinyl polymerizations), curing agent (unsaturated polyester resins), and fumigant (when heated);BLOWING AGENT FOR ELASTOMERS & PLASTICS; INITIATOR FOR FREE RADICAL REACTIONS; CATALYST FOR VINYL POLYMERIZATIONS & FOR CURING UNSATURATED POLYESTER RESINS; AZOBISNITRILES ARE CARRIER GASES FOR FUMIGANTS. COMPOUND CONTAINING PERMETHRIN 10, 2,2'-AZOBISISOBUTYRONITRILE 80, & MOLDING AGENT 10 PARTS WAS GRANULATED. WHEN HEATED 92% OF PERMETHRIN GASIFIED.
|
| ADME/Pharmacokinetics |
Metabolism / Metabolites
IN ORGANISM, FORMS HCN WHICH IS FOUND IN BLOOD, LIVER & BRAIN. |
| Toxicity/Toxicokinetics |
Toxicity Data
LC (rat) > 12,000 mg/m3/4h Exposure Routes The substance can be absorbed into the body by ingestion. Symptoms Ingestion Exposure Headache. Nausea. Weakness. Convulsions. Adverse Effects Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation. Nephrotoxin - The chemical is potentially toxic to the kidneys in the occupational setting. Other Poison - Chemical Asphyxiant rat LD50 oral 100 mg/kg BEHAVIORAL: GENERAL ANESTHETIC; BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY); BEHAVIORAL: ATAXIA National Technical Information Service., OTS0555369 rat LC inhalation >12 gm/m3/4H SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE; BEHAVIORAL: EXCITEMENT National Technical Information Service., OTS0555369 rat LD50 intraperitoneal 25 mg/kg BEHAVIORAL: GENERAL ANESTHETIC; BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY); BEHAVIORAL: ATAXIA National Technical Information Service., OTS0555369 rat LDLo subcutaneous 30 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD; LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Archiv fuer Toxikologie., 16(367), 1957 mouse LD50 oral 700 mg/kg Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals, 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989, 11(146), 1989 |
| References |
[1]. https://pubchem.ncbi.nlm.nih.gov/compound/6547
|
| Additional Infomation |
Insoluble in water and denser than water. Moderately toxic by ingestion. Readily ignited by sparks or flames. Burns intensely and persistently. Toxic oxides of nitrogen produced during combustion. Used as a catalyst, in vinyl polymerizations and a blowing agent for plastics.
(E)-Azobis(isobutyronitrile) is a monoazo compound. |
| Molecular Formula |
C8H12N4
|
|---|---|
| Molecular Weight |
164.2077
|
| Exact Mass |
164.106
|
| CAS # |
78-67-1
|
| PubChem CID |
6547
|
| Appearance |
CRYSTALS FROM ETHANOL + WATER
WHITE POWDER |
| Density |
1.0±0.1 g/cm3
|
| Boiling Point |
236.2±25.0 °C at 760 mmHg
|
| Melting Point |
102-104 °C (dec.)(lit.)
|
| Flash Point |
96.6±23.2 °C
|
| Vapour Pressure |
0.0±0.5 mmHg at 25°C
|
| Index of Refraction |
1.491
|
| LogP |
1.26
|
| Hydrogen Bond Donor Count |
0
|
| Hydrogen Bond Acceptor Count |
4
|
| Rotatable Bond Count |
2
|
| Heavy Atom Count |
12
|
| Complexity |
251
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
N(/C(C#N)(C([H])([H])[H])C([H])([H])[H])=N\C(C#N)(C([H])([H])[H])C([H])([H])[H]
|
| InChi Key |
OZAIFHULBGXAKX-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C8H12N4/c1-7(2,5-9)11-12-8(3,4)6-10/h1-4H3
|
| Chemical Name |
2-(2-cyanopropan-2-yldiazenyl)-2-methylpropanenitrile
|
| Synonyms |
78-67-1; 2,2'-Azobis(2-methylpropionitrile); Azobisisobutyronitrile; AIBN; 2,2'-Azobisisobutyronitrile; Genitron; 2,2'-AZOBIS(ISOBUTYRONITRILE); Aivn;
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
|
|---|
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 6.0898 mL | 30.4488 mL | 60.8976 mL | |
| 5 mM | 1.2180 mL | 6.0898 mL | 12.1795 mL | |
| 10 mM | 0.6090 mL | 3.0449 mL | 6.0898 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
COA