| Size | Price | |
|---|---|---|
| 500mg | ||
| 1g | ||
| Other Sizes |
| References | |
|---|---|
| Additional Infomation |
Sodium lactate is an organic sodium salt whose counterion is lactate. It can be used as a food preservative and a food acidity regulator. It is an organic sodium salt and also a lactate salt. It contains lactate. Sodium lactate is the sodium salt of racemic or inactive lactic acid, and has alkalizing and electrolyte-replenishing effects. After metabolism, sodium lactate is converted to bicarbonate, thereby increasing plasma bicarbonate concentration, promoting the clearance of hydrogen ions and lactate from the blood, and leading to an increase in blood pH. Compound sodium lactate solution is a multi-electrolyte isotonic crystalloid solution for intravenous infusion, containing sodium chloride, potassium chloride, calcium chloride dihydrate, and sodium lactate. It can restore electrolyte balance, regulate pH, and provide hydration to replenish body fluids. After intravenous infusion, compound sodium lactate solution can replenish lost body fluids and electrolytes, thereby replenishing hydration and normalizing electrolyte concentrations. Furthermore, the conversion of sodium lactate to bicarbonate increases plasma bicarbonate levels, thereby promoting the clearance of hydrogen ions from the blood, increasing blood pH, and restoring acid-base balance to normal. Sodium lactate is the sodium salt of racemic or inactive lactic acid. It is a hygroscopic drug that can be administered intravenously as a systemic and urinary alkalizing agent. See also: Sodium cation (with the active moiety)... See more...
|
| Molecular Formula |
13C3H5NAO3
|
|---|---|
| Molecular Weight |
115.0377
|
| Exact Mass |
115.024
|
| CAS # |
201595-71-3
|
| Related CAS # |
L-Lactic acid-13C3;87684-87-5
|
| PubChem CID |
23666456
|
| Appearance |
Colorless to light yellow liquid
|
| Melting Point |
163-165 ℃(lit.)
|
| Hydrogen Bond Donor Count |
1
|
| Hydrogen Bond Acceptor Count |
3
|
| Rotatable Bond Count |
1
|
| Heavy Atom Count |
7
|
| Complexity |
63.2
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
[Na+].[13CH3][13C@@H]([13C](=O)[O-])O
|
| InChi Key |
NGSFWBMYFKHRBD-UHFFFAOYSA-M
|
| InChi Code |
InChI=1S/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1
|
| Chemical Name |
sodium;2-hydroxypropanoate
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
DMSO : ~100 mg/mL (~869.26 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (21.73 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (21.73 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. View More
Solubility in Formulation 3: ≥ 2.5 mg/mL (21.73 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 8.6926 mL | 43.4631 mL | 86.9263 mL | |
| 5 mM | 1.7385 mL | 8.6926 mL | 17.3853 mL | |
| 10 mM | 0.8693 mL | 4.3463 mL | 8.6926 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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