| Size | Price | |
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| Other Sizes |
| Toxicity/Toxicokinetics |
Interactions
In early chicks, dietary supplementation with D,L-α-tocopherol acetate completely prevents alcohol-induced nutritional encephalomalacia. When using surfactants (e.g., Tween 80), alcohol emulsions exhibit phytotoxicity only in young meristems. Without surfactants, C11 alcohols and esters show non-selective tissue-killing effects. Non-human Toxicity Values Rabbit skin LD50 >5 g/kg /from table/ Rat oral LD50 3000 mg/kg Guinea pig skin LD50 >20 g/kg |
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| References | |
| Additional Infomation |
1-Undecyl alcohol is a water-white liquid with a slight odor. Flash point 250°F (121°C). Slightly soluble in water. The U.S. Department of Transportation (DOT) lists it as a marine pollutant. Immediate measures should be taken to limit its spread into the environment. As a liquid, it readily seeps into soil, contaminating groundwater or streams. It is slightly irritating to eyes and skin. 1-Undecyl alcohol is a primary alcohol, formed by replacing undecane with a hydroxyl group at the 1-position. It is a plant metabolite and flavoring agent. It is a primary alcohol and also a type of undecyl alcohol. 1-Undecyl alcohol has been reported to be found in Listeria guineensis, Pelargonium endlicherianum, and other organisms with relevant data. Undecyl alcohol is a metabolite found in or produced by Saccharomyces cerevisiae. Mechanism of Action: ...Undecyl alcohol is the most potent fungicide, followed by decanol. Time-sterilization curve studies showed that undecyl alcohol had a bactericidal effect on Saccharomyces cerevisiae at any growth stage and was unaffected by pH. The tested alcohols inhibited glucose-induced acidification by inhibiting plasma membrane H(+)-ATPase. The main antifungal activity of amphiphilic medium-chain (C(9)-C(12)) alkanols stemmed from their ability as nonionic surfactants to disrupt the natural membrane-related functions of integrins.
|
| Molecular Formula |
C₁₁H₂₄O
|
|---|---|
| Molecular Weight |
172.31
|
| Exact Mass |
172.182
|
| CAS # |
112-42-5
|
| Related CAS # |
1-Undecanol-d23;349553-88-4;1-Undecanol-d4;1219803-47-0
|
| PubChem CID |
8184
|
| Appearance |
Colorless liquid
|
| Density |
0.8±0.1 g/cm3
|
| Boiling Point |
243.2±3.0 °C at 760 mmHg
|
| Melting Point |
11 °C(lit.)
|
| Flash Point |
109.0±4.6 °C
|
| Vapour Pressure |
0.0±1.1 mmHg at 25°C
|
| Index of Refraction |
1.438
|
| LogP |
4.59
|
| Hydrogen Bond Donor Count |
1
|
| Hydrogen Bond Acceptor Count |
1
|
| Rotatable Bond Count |
9
|
| Heavy Atom Count |
12
|
| Complexity |
71.4
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
O([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
|
| InChi Key |
KJIOQYGWTQBHNH-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C11H24O/c1-2-3-4-5-6-7-8-9-10-11-12/h12H,2-11H2,1H3
|
| Chemical Name |
undecan-1-ol
|
| Synonyms |
1Undecanol; 1 Undecanol
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
DMSO : ~100 mg/mL (~580.35 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 4.55 mg/mL (26.41 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 45.5 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (14.51 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. View More
Solubility in Formulation 3: ≥ 2.5 mg/mL (14.51 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 5.8035 mL | 29.0175 mL | 58.0349 mL | |
| 5 mM | 1.1607 mL | 5.8035 mL | 11.6070 mL | |
| 10 mM | 0.5803 mL | 2.9017 mL | 5.8035 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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