| Size | Price | Stock | Qty |
|---|---|---|---|
| 100mg |
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| 250mg |
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| 500mg |
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| 1g |
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| Targets |
1-Palmitoyl-sn-glycero-3-phosphocholine does not have a specific biological target as a drug; it is a phospholipid used in biochemical and formulation research. As a lysophospholipid, it can act as a signaling molecule and is involved in lipid metabolism and membrane dynamics. It is used in the design of fluorescent probes for studying membrane properties.
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|---|---|
| ln Vitro |
1-Palmitoyl-sn-glycero-3-phosphocholine is not evaluated for biological activity as a drug; it is a phospholipid used in research. It is used in the design of fluorescent probes and as a biochemical tool for studying lipid metabolism and membrane dynamics.
|
| ln Vivo |
1-Palmitoyl-sn-glycero-3-phosphocholine is not evaluated for in vivo biological activity as a drug; it is a phospholipid used in research. It may be used in animal studies to investigate lipid metabolism or as a component of liposomes for drug delivery.
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| Enzyme Assay |
There are no specific in vitro enzyme or receptor binding assays for 1-Palmitoyl-sn-glycero-3-phosphocholine as a drug target. As a phospholipid, it is characterized by its chemical properties, including molecular formula (C24H50NO7P) and molecular weight (495.6).
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| Cell Assay |
There are no specific in vitro cellular assays for 1-Palmitoyl-sn-glycero-3-phosphocholine as a pharmacologically active compound. As a lysophospholipid, it can be used in cell culture to study lipid signaling and membrane dynamics.
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| Animal Protocol |
There are no specific in vivo animal studies for 1-Palmitoyl-sn-glycero-3-phosphocholine as a pharmacologically active compound. As a lipid, it may be used in metabolic studies or as a component of lipid-based formulations.
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| ADME/Pharmacokinetics |
Pharmacokinetic properties of 1-Palmitoyl-sn-glycero-3-phosphocholine are not applicable, as it is a phospholipid rather than a drug. The compound is not intended for administration as a therapeutic agent.
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| Toxicity/Toxicokinetics |
The toxicity profile of 1-Palmitoyl-sn-glycero-3-phosphocholine is not extensively reported. As a phospholipid, it is generally considered safe for research use. The compound is not intended for human therapeutic use.
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| References |
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| Additional Infomation |
1-Hexadecanoyl-sn-glycerol-3-phosphate choline is a lysophosphatidylcholine 16:0, wherein the hexadecanoyl group (palmitoyl group) is attached to the 1-position of the glycerol moiety. It is a mouse metabolite. It is a lysophosphatidylcholine 16:0, and also a 1-O-acyl-sn-glycerol-3-phosphate choline. 1-Palmitoyl-sn-glycerol-3-phosphate choline has been reported in Drosophila melanogaster, Blephalopoda japonica, and other organisms with relevant data. PC (16:0/0:0) is a metabolite found or produced in Saccharomyces cerevisiae.
1-Palmitoyl-sn-glycero-3-phosphocholine (CAS 17364-16-8) is a lysophosphatidylcholine with a palmitoyl group at the sn-1 position. It has a molecular formula of C24H50NO7P and a molecular weight of 495.6. The compound is used in the design of fluorescent probes and as a biochemical tool for studying lipid metabolism and membrane dynamics. It is available for research purposes only. |
| Molecular Formula |
C24H50NO7P-
|
|---|---|
| Molecular Weight |
495.6301
|
| Exact Mass |
495.332
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| CAS # |
17364-16-8
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| PubChem CID |
460602
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| Appearance |
White to off-white solid powder
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| LogP |
5.649
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| Hydrogen Bond Donor Count |
1
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| Hydrogen Bond Acceptor Count |
7
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| Rotatable Bond Count |
24
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| Heavy Atom Count |
33
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| Complexity |
517
|
| Defined Atom Stereocenter Count |
1
|
| SMILES |
CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)O
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| InChi Key |
ASWBNKHCZGQVJV-HSZRJFAPSA-N
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| InChi Code |
InChI=1S/C24H50NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(27)30-21-23(26)22-32-33(28,29)31-20-19-25(2,3)4/h23,26H,5-22H2,1-4H3/t23-/m1/s1
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| Chemical Name |
[(2R)-3-hexadecanoyloxy-2-hydroxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture and light. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
H2O : ~50 mg/mL (~100.88 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 50 mg/mL (100.88 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.0176 mL | 10.0882 mL | 20.1763 mL | |
| 5 mM | 0.4035 mL | 2.0176 mL | 4.0353 mL | |
| 10 mM | 0.2018 mL | 1.0088 mL | 2.0176 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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