| Size | Price | |
|---|---|---|
| 500mg | ||
| 1g | ||
| Other Sizes |
| ln Vivo |
Methiazoline (250–4000 g ai ha-1; foliar spraying using a pressurized carbon dioxide tracked sprayer at a rate of 300 L ha-1 and a pressure of 280 kPa) was safe for all tested turfgrasses at doses ≤1000 g ai ha-1. Temporary, recoverable phytotoxicity was observed at higher doses (2000–4000 g ai ha-1), which subsided or diminished within 6 weeks after application [1]. Methiazoline (500–2000 g ha-1; foliar spraying) inhibited grain yield in annual bluegrass in a dose-dependent manner. At the same dose, the reduction in grain number was greater than the reduction in grain length, with an inhibition rate of over 80% at 2000 g ha-1 [1]. Methionine (500-2000 g ha⁻¹; foliar + soil spray; foliar spray only; soil drip application only) has a herbicidal activity against annual Kentucky bluegrass that depends entirely on soil absorption, as foliar application alone is ineffective, while soil application alone is comparable to foliar + soil combined application[1]. Methionine (500-1000 g ai ha⁻¹; foliar spray with hand sprayer, 1000 L ha⁻¹; spray once every 3 weeks; spray a total of 12 times) has the best control effect on annual Kentucky bluegrass when applied in autumn (about 90-100%), but it can cause temporary, reversible creeping bentgrass damage, which will subside in June; while spring application has a lower control effect (40-60%) and does not cause persistent damage[1].
|
|---|---|
| References |
| Molecular Formula |
C17H17F2NO2S
|
|---|---|
| Molecular Weight |
337.38
|
| CAS # |
403640-27-7
|
| Appearance |
Typically exists as solids at room temperature
|
| SMILES |
FC1=CC=CC(F)=C1COCC2(ON=C(C=3SC=CC3C)C2)C
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
|
|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.9640 mL | 14.8201 mL | 29.6402 mL | |
| 5 mM | 0.5928 mL | 2.9640 mL | 5.9280 mL | |
| 10 mM | 0.2964 mL | 1.4820 mL | 2.9640 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
