Molecular Glues

Molecular Glues related products

Cat No.	Product Name	CAS No.	Product Description
V115220	dRRM-1	253328-68-6	dRRM-1 is a DCAF15-dependent gel degrader for RBM39 and RBM23 molecules.
V87960	ER degrader 9	3023359-75-0	ER degrader 9 (compound 1) is a bifunctional molecule and a potent estrogen receptor (ER) degrader with a DC50 of ≤10 nM in MCF-7 cells.
V115651	GSPT1 degrader-13		GSPT1 Degrader-13 is a selective molecular adhesive GSPT1 degrader.
V115840	GSPT1 degrader-16	3060504-68-6	GSPT1 degrader-16 (compound Lib-B-18J) is a highly efficient and selective cereblon-based molecular gel degrader that targets G1-to-S phase transition protein 1 (GSPT1).
V87958	GSPT1 degrader-4	3034764-32-1	GSPT1 degrader-4 (3) is a molecular glue for GSPT1 (DC50 of 25.4 nM) with an IC50 value of 39 nM in CAL51 cells.
V136982	GSPT1 degrader-7	3082942-43-3	GSPT1 degrader-7 is a molecular gel degrader that targets GSPT1.
V137754	IBA-12		IBA-12 is an IKZF2 molecular gel/PROTAC degrader with a DC50 of 276.2 nM in Jurkat cells, a DC50 of 461.8 nM in Mino cells, and an IC50 of 179.9 nM.
V138465	KMG-1068	3113750-79-8	KMG-1068 is a molecular adhesive that is biodegradable by GSPT1/2.
V87043	Lirodegimod (KT-333)	2502186-79-8	KT-333 is a molecular glue that degrades STAT3 protein.
V86770	Pan-RAS-IN-5		Pan-RAS-IN-5 (compound 7A) is a molecular glue that can form a ternary complex with cyclophilin A (CYPA) and RAS (ON) proteins.
V146199	TNG961		TNG961 is a selectively orally active CRBN-mediated HBS1L molecular gel degrader.
V146889	VAV1 degrader-4	3119457-09-6	VAV1 degrader-4 is a VAV1 molecular gel degrader with a DC50 value of 3.93 nM for VAV1 in Jurkat cells.
V147007	Voclosporin-d4		Voclosporin-d4 is a deuterated Voclosporin.
V1858	Cyclosporin A (Cyclosporine A)	59865-13-3	Cyclosporin A (Cyclosporine A; CsA)is anaturally occuring cyclic polypeptide immunosuppressive agent and a calcineurin inhibitor, which binds to the cyclophilin and then inhibits calcineurin with IC50 of 7 nM in a cell-free assay.