E3 Ligase Ligand-Linker Conjugates

E3 Ligase Ligand-Linker Conjugates related products

Cat No.	Product Name	CAS No.	Product Description
V104289	(S)-Deoxy-thalidomide-2,7-diazaspiro[3.5]nonane-C-Pip		(S)-Deoxy-thalidomide-2,7-diazaspiro[3.5]nonane-C-Pip is an E3 ubiquitin ligase ligand + linker conjugate used in the synthesis of PROTAC FHD-609.
V110411	(S,R,S)-AHPC-C2-PEG3-NH2	2243090-28-8	(S,R,S)-AHPC-C2-PEG3-NH2 is an E3 ligase ligand-linker conjugate that can be used to synthesize PROTAC USP39 degrader-1.
V87922	(S,R,S)-AHPC-CO-C9-NH2	2349429-71-4	(S,R,S)-AHPC-CO-C9-NH2 is a Von Hippel-Lindau (VHL) amino building block that can be used to synthesize the E3 ligase ligands required for PROTACs.
V99933	(S,R,S)-AHPC-CO-cyclohexane-C2		(S,R,S)-AHPC-CO-cyclohexane-C2 is an E3 ubiquitin ligase ligand-adapter conjugate.
V99917	(S,R,S)-AHPC-CO-cyclohexene-Bpin		SMARCA2/4-ligand-adaptor binder-5 is an E3 ubiquitin ligase ligand-adaptor binder.
V122243	(S,R,S)-AHPC-CO-PEG-C2-iodine	3057447-11-4	(S,R,S)-AHPC-CO-PEG-C2-iodine is an E3 ligase (VHL) ligand-linker conjugate that can be used to synthesize PROTACs, such as PROTAC FAK degrader 1.
V122248	(S,R,S)-AHPC-Me-amide-C-O-C5-Br		(S,R,S)-AHPC-Me-amide-CO-C5-Br contains a VHL ligand for an E3 ubiquitin ligase and a PROTAC linker.
V104243	(S,R,S)-AHPC-Me-amide-C9-acid	2376139-66-9	(S,R,S)-AHPC-Me-amide-C9-acid is an E3 ligase ligand-linker conjugate used in the synthesis of PROTAC SMARCA2 degrader-31.
V114022	(S,R,S)-AHPC-Me-C4-NH2 hydrochloride	2458219-89-9	(S,R,S)-AHPC-Me-C4-NH2 hydrochloride is an E3 ligand-linker conjugate comprising a VHL ligand and a linker based on (S,R,S)-AHPC.
V97358	(S,R,S)-AHPC-O-CF3-CO-cyclohexene-Bpin		(S,R,S)-AHPC-O-CF3-CO-cyclohexene-Bpin is an E3 ubiquitinase ligand + adaptor conjugate.
V82360	(−)-N-Hydroxyapiosporamide (NHAP)	1205676-02-3	(−)-N-Hydroxyapiosporamide (NHAP) is an alkaloid and an NF-κB inhibitor (antagonist) with potent anticancer effect in vitro and in vivo.
V112588	2-(2,6-Dioxopiperidin-3-yl)phthalimidine-O-piperidine	2222115-81-1	2-(2,6-dioxadiazine-3-yl)phthalimide-O-piperidine is an E3 ligand-linker conjugate containing a CRBN ligand and a linker, which can be used to synthesize PROTAC.
V113107	2-(2,6-Dioxopiperidin-3-yl)phthalimidine-Piperazine-piperidine dihydrochloride	2369981-22-4	2-(2,6-dioxadiazin-3-yl)phthalimide-piperazine-piperidine dihydrochloride is an E3 ligand-linker conjugate containing a CRBN-based ligand and a linker, which can be used to synthesize PROTAC.
V112965	6-(2,6-Dioxopiperidin-3-yl)-2-(piperazin-1-yl)-5H-pyrrolo[3,4-d]pyrimidine-5,7(6H)-dione hydrochloride	2229738-21-8	6-(2,6-dioxadiazin-3-yl)-2-(piperazin-1-yl)-5H-pyrrolo[3,4-d]pyrimidine-5,7(6H)-dione hydrochloride is an E3 ligand-linker conjugate containing a CRBN ligand and a linker, which can be used to synthesize PROTAC.
V97421	Ac-NH-(S,R,S)-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo		Ac-NH-(S,R,S)-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo is an E3 ligase ligand-linker conjugate.
V82339	Alkaline phosphatase (alkaline phosphatase; Apase)	9001-78-9	Alkaline phosphatase (Apase) is a membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH.
V82346	ALV2	2438124-95-7	ALV2 is a potent and specific Helios degrader.
V82362	Amino-PEG7-t-butyl ester	2428400-07-9	Amino-PEG7-t-butyl ester is a PROTAC (PROteolysis TArgeting Chimera) linker of the PEG category, may be utilized to prepare PROTAC protein degraders.
V82487	Azido-PEG4-azide	182760-73-2	Azido-PEG4-azide is a PROTAC (PROteolysis TArgeting Chimera) linker and belongs to the PEG (Polyethylene glycol) class.
V82469	Benzyl-PEG12-alcohol	2218463-17-1	Benzyl-PEG12-alcohol is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders.