Small Molecule-based Onco-immune Modulator Library
Small Molecule-based Onco-immune Modulator Library Chemical Structure
Product category: Screening Library
This product is for research use only, not for human use. We do not sell to patients.
| Size |
Price |
| 100uL/well (10 mM solution) |
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| 20uL/well (10 mM solution) |
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Official Supplier of:
- Business Relationship with 5000+ Clients Globally
- Major Universities, Research Institutions, Biotech & Pharma
- Citations by Top Journals: Nature, Cell, Science, etc.
Introduction
Small Molecule-based Onco-immune Modulator Library is a collection of 210 compounds targeting various onco-immunological targets such as PD-1/PD-L1, Sting, TLR, IDO, ROR, HPK, CCR, CXCR, etc, encompassing inhibitors, degraders, agonists, and other modulators. Small Molecule-based immunotherapy has the potential to revolutionize cancer treatment. Small Molecule-based Onco-immune Modulator Library includes various newly reported compounds, approved and investigational drugs. It can be used for high throughput screening (HTS) and high content screening (HCS). The compounds are structurally diverse and pharmacologically active. The bioactivity and safety for a portion of the compounds have been confirmed by preclinical and clinical studies.
Product Details
1. Form: Compounds in this library are in solid powder form or in pre-dissolved solutions.
2. Plate Layout:
96-well sample storage tube or 96-well plate with 1st and 12th column emptied.
384-well plate with the first 2 columns and the last 2 columns emptied.
3. Packaging & Container: 96- or 384-well plates sealed with peelable foil; 96-well format sample storage tube with screw cap.
4. Storage & Stability: store at -80°C for long term (1-2 years) and -20°C for short term (<1 year).
5. Shipping Condition: Blue ice for solutions; RT for solid powder form; or blue ice upon request.
Compound Library Composition
Kinase Inhibitor Library is composed of 210 compounds targeting a wide range of kinases such as KRAS, TPK, CDK, Akt, c-Kit, PDGFR, HPK, Flt3, VEGFR, BTK, EGFR, PI4K, PI3K, SK etc. The Kinase Inhibitor Library can be used for identification of new therapeutic agents, targets, and action mechanisms.
References
[1]. Acta Pharm Sin B. 2022 Dec;12(12):4287-4308.
