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100mg | ||
250mg | ||
500mg |
ln Vitro |
The most prevalent monounsaturated fertilizer (FA) in human fat cells and other tissues is oleic acid. In organs with high migration rates, oleic acid stimulates AMPK oil activation-mediated beta-oxidation, which in turn drives cell division and migration. Growth and death rates of low-proliferative tumors, including the MCF-7 cell line for breast cancer and the acid blocker SGC7901 [1].
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References |
[1]. Li S, et al. High metastaticgastric and breast cancer cells consume oleic acid in an AMPK dependent manner. PLoS One. 2014 May 13;9(5):e97330.
[2]. Jack-Hays MG, et al. Activation of Na+/K(+)-ATPase by fatty acids, acylglycerols, and related amphiphiles: structure-activity relationship. Biochim Biophys Acta. 1996 Feb 21;1279(1):43-8. |
Molecular Formula |
C18H33NAO2
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Molecular Weight |
304.443
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CAS # |
143-19-1
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Related CAS # |
Oleic acid;112-80-1
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SMILES |
[Na+].[O-]C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/C(/[H])=C(\[H])/C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=O
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Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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Solubility (In Vitro) |
H2O : ~25 mg/mL (~82.12 mM)
DMSO :< 1 mg/mL |
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Solubility (In Vivo) |
Solubility in Formulation 1: 9.09 mg/mL (29.86 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication (<60°C).
 (Please use freshly prepared in vivo formulations for optimal results.) |
Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
1 mM | 3.2847 mL | 16.4236 mL | 32.8472 mL | |
5 mM | 0.6569 mL | 3.2847 mL | 6.5694 mL | |
10 mM | 0.3285 mL | 1.6424 mL | 3.2847 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration: mg/mL;
Method for preparing DMSO stock solution: mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation::Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.