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      JNJ-26854165 (Serdemetan)
      JNJ-26854165 (Serdemetan)
      Catalog No： V0013
      CAS No. (CAS Registry Number)： 881202-45-5
      Description: Serdemetan (formerly JNJ26854165; JNJ-26854165; JNJ 26854165), originally developed as an activator of p53, is now considered to be a novel, potent and orally bioactive antagonist of...
      Pifithrin-α (PFTα) HBr
      Pifithrin-α (PFTα) HBr
      Catalog No： V0014
      CAS No. (CAS Registry Number)： 63208-82-2
      Description: Pifithrin-α HBr ((PFTα hydrobromide; PFT-α) is a novel and potent inhibitor of p53, acting by inhibiting p53 protein transcription and p53-dependent transactivation of p53-responsive...
      RITA (NSC 652287)
      RITA (NSC 652287)
      Catalog No： V0015
      CAS No. (CAS Registry Number)： 213261-59-7
      Description: RITA (also known as NSC-652287) is a novel and potent inhibitor of p53-HDM-2 protein-protein interaction with potential anticancer activity. It binds to p53dN with a Kd of 1.5 nM, an...
      Tenovin-1
      Tenovin-1
      Catalog No： V0016
      CAS No. (CAS Registry Number)： 380315-80-0
      Description: Tenovin-1, a small molecule compound discovered by a cell-based screen, is a novel and potent activator of p53 that protects against MDM2-mediated p53 degradation. It acts by inhibit...
      NSC 319726
      NSC 319726
      Catalog No： V0017
      CAS No. (CAS Registry Number)： 71555-25-4
      Description: NSC319726 is a novel and potent p53(R175) mutant reactivator with with potential anticancer activity. It exhibits growth inhibition in cells expressing mutant p53 (IC50 of 8 nM ...
      NSC59984
      NSC59984
      Catalog No： V0018
      CAS No. (CAS Registry Number)： 803647-40-7
      Description: NSC59984 is a novel and potent activator of p53 with potential anticancer activity. It acts via induction of mutant p53 protein degradation and p73 activation. References: ...
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