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    Catalog No: V3448
    CAS No. (CAS Registry Number): 1883727-34-1
    Description: AMG-176 is a novel, potent, selective and orally bioavailable inhibitor of MCL-1 (myeloid cell leukemia-1) with a Ki of 0.13 nM. AMG-176 has potential pro-apoptotic and ant...
    Catalog No: V3449
    CAS No. (CAS Registry Number): 2296729-00-3
    Description: AMG-510 (Sotorasib) is a novel, potent and covalent inhibitor of KRAS G12C. KRAS gene mutations are common in pancreatic cancer, lung adenocarcinoma, colorectal cancer, gal...
    Catalog No: V3451
    CAS No. (CAS Registry Number): 1392399-03-9 (HCl salt)
    Description: BIX01294 triHCl (the tri-hydrochloride salt of BIX01294) is a novel and potent inhibitor of G9a histone methyltransferase with IC50 of 2.7 μM in a cell-free assay. BIX-01294 was discovere...
    Catalog No: V3452
    CAS No. (CAS Registry Number): 1197196-48-7
    Description: UNC0224 is a novel, potent and selective G9a histone methyltransferase inhibitor with IC50 of 15 nM in in the G9a Thioglo assay. In an ITC experiment to measure the binding affn...
    Catalog No: V3453
    CAS No. (CAS Registry Number): 1238673-32-9
    Description: UNC0321 is a novel, potent and selective G9a histone methyltransferase inhibitor with Ki of 63 pM, UNC0321 was discovered by optimizing the 7-dimethylaminopropoxy side chain on ...
    Catalog No: V3454
    CAS No. (CAS Registry Number): 1228184-65-3
    Description: BIX-01338 is a novel and potent histone lysine methyltransferase G9a inhibitor with an IC50 value of 4.7µM. BIX01338 was discovered by high-throughput screening a...
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