Vitamin D Related/Nuclear Receptor

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Signaling Pathways
Apoptosis
- ♦ Bcl-2(19)
- ♦ p53(12)
- ♦ Caspase(17)
- ♦ TNFa(16)
- ♦ Mdm2(17)
- ♦ c-RET(4)
- ♦ IAP(7)
- ♦ PERK(4)
- ♦ PD-1/PD-L1(15)
- ♦ Survivin(1)
- ♦ Apoptosis(27)
- ♦ RIP kinase(7)
- ♦ ROS(1)
- ♦ Cytohesin(1)
- ♦ Ras(1)
- ♦ Thymidylate Synthase(3)
- ♦ DAPK(1)
- ♦ Ferroptosis(1)
- ♦ ASK(1)
- ♦ FKBP(1)
- ♦ Ferroptosis(1)
PI3K/Akt/mTOR
- ♦ PI3K (72)
- ♦ Akt (26)
- ♦ mTOR (25)
- ♦ GSK-3 (18)
- ♦ ATM/ATR (0)
- ♦ PDK-1 (4)
- ♦ S6 kinase (6)
- ♦ AMPK (14)
- ♦ DNA-PK (5)
- ♦ PTEN(1)
- ♦ PDPK1(1)
- ♦ NUDIX(1)
- ♦ PDHK(1)
- ♦ PI4K(1)
- ♦ PP2A(1)
Epigenetics
- ♦ HDAC(6)
- ♦ HIF(7)
- ♦ PARP(0)
- ♦ JAK(40)
- ♦ Aurora Kinase(23)
- ♦ Histone Acetyltransferase (9)
- ♦ Histone Demethylase(15)
- ♦ Histone Methyltransferase (46)
- ♦ DNA Methyltransferase(9)
- ♦ Epigenetic Reader Domain (30)
- ♦ Sirtuin (13)
- ♦ Pim (6)
- ♦ PKC(8)
- ♦ SMYD(1)
- ♦ Methionine Adenosyltransferase(1)
- ♦ MicroRNA(2)
- ♦ AMPK(1)
- ♦ Protein Arginine Deiminase(2)
MAPK
- ♦ MEK(19)
- ♦ ERK(16)
- ♦ Raf(18)
- ♦ JNK(15)
- ♦ p38 MAPK(20)
- ♦ RSK(3)
- ♦ Mixed Lineage Kinase(1)
- ♦ KLF(1)
- ♦ MNK(2)
Protein Tyrosine Kinase
- ♦ VEGFR (58)
- ♦ EGFR (49)
- ♦ PDGFR(17)
- ♦ c-MET (19)
- ♦ HER-2(2)
- ♦ ALK(16)
- ♦ FLT3 (11)
- ♦ FGFR (15)
- ♦ IFG-1R(10)
- ♦ c-Kit(6)
- ♦ Tie-2(1)
- ♦ CSF-1R(3)
- ♦ TAM Receptor (7)
- ♦ Trk receptor(4)
- ♦ c-RET(0)
- ♦ Axl(1)
- ♦ Bcr-Abl(4)
- ♦ Ephrin Receptor(1)
- ♦ Pyk2(1)
- ♦ c-Fms(4)
- ♦ DDR(1)
- ♦ FLT3(0)
- ♦ HER2(1)
- ♦ Src(2)
- ♦ Syk(1)
- ♦ DYRK(3)
- ♦ FAK(1)
Angiogenesis
- ♦ VEGFR (1)
- ♦ EGFR (1)
- ♦ PDGFR (0)
- ♦ HIF (3)
- ♦ HER-2 (0)
- ♦ JAK (0)
- ♦ FLT3 (0)
- ♦ FGFR (0)
- ♦ BTK (10)
- ♦ Syk(6)
- ♦ FAK (8)
- ♦ Src (8)
- ♦ Bcr-Abl (10)
- ♦ VDA (3)
- ♦ ALK(1)
Proteases
- ♦ Proteasome (13)
- ♦ Cysteine Protease (12)
- ♦ Serine Protease(6)
- ♦ Gamma-secretase (10)
- ♦ HCV Protease (5)
- ♦ HIV Protease(7)
- ♦ MMP (7)
- ♦ DPP-4 (9)
- ♦ Caspase (0)
- ♦ Acyltransferase(1)
- ♦ Tyrosinase(1)
- ♦ Glutaminase(2)
- ♦ Thrombin(3)
- ♦ 3C-Like Protease(1)
NF-kB
- ♦ NOD1 (2)
- ♦ IκB/IKK(20)
- ♦ NF-κB(37)
- ♦ HDAC (0)
- ♦ ROS(1)
Autophagy
- ♦ Autophagy (34)
- ♦ LRRK2 (6)
- ♦ ULK(2)
- ♦ Mitophagy(1)
JAK/STAT
- ♦ JAK (2)
- ♦ STAT(5)
- ♦ EGFR (11)
- ♦ Pim (4)
Metabolism
- ♦ PDE (28)
- ♦ P450 (e.g. CYP) (27)
- ♦ PPAR (18)
- ♦ Phospholipase (8)
- ♦ DHFR(6)
- ♦ Dehydrogenase (24)
- ♦ HSP (20)
- ♦ Carbonic Anhydrase (16)
- ♦ MAO (2)
- ♦ FAAH (6)
- ♦ CETP(4)
- ♦ Transferase (10)
- ♦ HMG-CoA Reductase(11)
- ♦ Hydroxylase (8)
- ♦ IDO (7)
- ♦ Retinoid Receptor (8)
- ♦ Factor Xa (5)
- ♦ AhR (3)
- ♦ Ferroptosis(3)
- ♦ Casein Kinase (7)
- ♦ NAMPT (3)
- ♦ Glucosylceramide Synthase(2)
- ♦ Aldose Reductase(1)
- ♦ ATP-citrate lyase(1)
- ♦ Carbohydrate Metabolism(1)
- ♦ FXR(5)
- ♦ IAP(1)
- ♦ Lipoxygenase(5)
- ♦ Mitochondrial Metabolism(1)
- ♦ PCSK9(2)
- ♦ Phosphorylase(1)
- ♦ Serine hydrolase(1)
- ♦ SGK(1)
- ♦ SCD(1)
- ♦ Vitamin(9)
- ♦ Acyltransferase(2)
- ♦ CAR(2)
- ♦ ROR(3)
- ♦ PRMT(1)
- ♦ PGC-1α(1)
- ♦ Lipase(1)
- ♦ OXPHOS(2)
- ♦ Peroxidases(2)
- ♦ Phosphatase(2)
- ♦ Decarboxylase(3)
- ♦ Prostaglandin Receptor(1)
- ♦ Serine/threonin kinase(2)
- ♦ Fatty Acid Synthase(3)
- ♦ THR(2)
- ♦ Glutathione(1)
- ♦ CPT(1)
- ♦ Acetyl-CoA Carboxylase(1)
- ♦ AChR(1)
- ♦ cGAS(1)
Neuronal Signaling
- ♦ 5-HT Receptor (3)
- ♦ COX (41)
- ♦ GluR (20)
- ♦ Adrenergic Receptor(11)
- ♦ AChR Receptor (62)
- ♦ Histamine Receptor (4)
- ♦ Dopamine Receptor (8)
- ♦ Opioid Receptor (3)
- ♦ GABA Receptor (14)
- ♦ P-gp (0)
- ♦ CaMK (10)
- ♦ P2 Receptor (8)
- ♦ OX Receptor (1)
- ♦ MT Receptor (0)
- ♦ BACE (2)
- ♦ Gamma-secretase (0)
- ♦ Beta Amyloid (13)
- ♦ Monoamine Oxidase(5)
- ♦ P2Y Receptor(1)
- ♦ NMDAR(3)
- ♦ γ-secretase(1)
- ♦ Calcium Channel(3)
- ♦ Serotonin Transporter(4)
- ♦ Transthyretin (TTR)(1)
- ♦ Notch(4)
- ♦ ChE(6)
- ♦ BChE(1)
- ♦ Glucosylceramide Synthase(1)
- ♦ AAK1(1)
- ♦ Dopamine Transporter(2)
- ♦ Sigma Receptor(2)
- ♦ Tau Protein(1)
Ubiquitin
- ♦ E2 conjugating (2)
- ♦ p97 (3)
- ♦ E3 Ligase (2)
- ♦ DUB (13)
- ♦ Proteasome (0)
- ♦ E1 Activating(2)
Stem Cells/Wnt
- ♦ Hedgehog/Smoothened ROCK (2)
- ♦ ROCK(0)
- ♦ Wnt/beta-catenin (13)
- ♦ Gamma-secretase (0)
- ♦ Casein Kinase (3)
- ♦ TGF–beta/Smad (1)
- ♦ STAT (9)
- ♦ JAK (0)
- ♦ GSK-3 (1)
- ♦ Smo(2)
- ♦ PKA(1)
- ♦ Oct(2)
- ♦ Porcupine(1)
- ♦ Hippo (MST)(1)
DNA Damage
- ♦ Telomerase(3)
- ♦ Topoisomerase (47)
- ♦ DNA/RNA Synthesis (84)
- ♦ HDAC (41)
- ♦ ATM/ATR (14)
- ♦ PARP (34)
- ♦ Sirtuin (1)
- ♦ DNA Stain(3)
- ♦ Nucleoside Antimetabolite/Analog(2)
- ♦ DNA alkylator(4)
- ♦ p97(1)
- ♦ CRISPR/Cas9(1)
- ♦ SMN(1)
- ♦ HSP(3)
- ♦ RNR(2)
- ♦ OGG1(1)
- ♦ RAD51(1)
GPCR & G Protein
- ♦ cAMP (3)
- ♦ Adenosine Receptor (24)
- ♦ Vasopressin Receptor (7)
- ♦ CXCR (13)
- ♦ CaSR (4)
- ♦ PAFR (2)
- ♦ CGRP Receptor (1)
- ♦ LPA Receptor (2)
- ♦ SGLT (6)
- ♦ S1P Receptor (11)
- ♦ Endothelin Receptor (10)
- ♦ Cannabinoid Receptor (13)
- ♦ 5-HT Receptor (101)
- ♦ Adrenergic Receptor (83)
- ♦ Histamine Receptor (57)
- ♦ Dopamine Receptor (59)
- ♦ Opioid Receptor (17)
- ♦ Hedgehog/Smoothened ROCK (11)
- ♦ OX Receptor (8)
- ♦ MT Receptor (2)
- ♦ Guanylate Cyclase(6)
- ♦ LPL Receptor(10)
- ♦ NPY receptor(1)
- ♦ Angiotensin Receptor(10)
- ♦ Free Fatty Acid Receptor(4)
- ♦ GnRH Receptor(4)
- ♦ GPR(14)
- ♦ Leukotriene Receptor(2)
- ♦ mAChR(16)
- ♦ Neurotensin Receptor(1)
- ♦ Prostaglandin Receptor(11)
- ♦ Sigma Receptor(1)
- ♦ PAR(4)
- ♦ CCR(2)
- ♦ GCGR(8)
- ♦ GHSR(2)
- ♦ GPCR19(2)
- ♦ LTR(1)
- ♦ mGluR(10)
- ♦ PKD(1)
- ♦ Ras(4)
- ♦ CCK receptor(4)
- ♦ Melatonin Receptor(2)
- ♦ Formyl Peptide Receptor(1)
- ♦ G protein-coupled Bile Acid Receptor(1)
- ♦ Melanocortin Receptor(3)
- ♦ Neurokinin Receptor(2)
- ♦ Oxytocin Receptor(1)
- ♦ Somatostatin Receptor(2)
- ♦ Adenylate Cyclase(2)
- ♦ Bradykinin Receptor(2)
- ♦ P2Y Receptor(1)
- ♦ Urotensin Receptor(1)
- ♦ TSH Receptor(1)
- ♦ PKG(1)
TGF-beta/Smad
- ♦ MT Receptor (20)
- ♦ Bcr-Abl (0)
- ♦ ROCK (20)
- ♦ PKC (11)
- ♦ TGF-β Receptor(7)
Cell Cycle
- ♦ CDK (55)
- ♦ Rho (17)
- ♦ PLK (14)
- ♦ Chk (8)
- ♦ Aurora Kinase (0)
- ♦ ROCK (4)
- ♦ PD-1/PD-L1 (0)
- ♦ c-Myc (4)
- ♦ Wee1 (1)
- ♦ APC (2)
- ♦ HSP(3)
- ♦ Microtubule/Tubulin(22)
- ♦ HDAC(5)
- ♦ PPAR(8)
- ♦ Eukaryotic Initiation Factor(1)
- ♦ Topoisomerase(4)
- ♦ Ras(2)
- ♦ Mps1(1)
- ♦ Kinesin(3)
- ♦ PAK(3)
- ♦ PERK(1)
- ♦ Antifolate(2)
- ♦ TOPK(1)
- ♦ PARP(1)
- ♦ LIMK(1)
- ♦ G-quadruplex(1)
Cytoskeletal Signaling
- ♦ Bcr-Abl(1)
- ♦ Wnt/beta-catenin (10)
- ♦ PKC (0)
- ♦ FAK(0)
- ♦ HSP (1)
- ♦ Dynamin (3)
- ♦ PAK (4)
- ♦ Integrin (16)
- ♦ Microtubule Associated(25)
- ♦ Kinesin (6)
- ♦ MLCK(1)
- ♦ Gap Junction Protein(3)
- ♦ Myosin(2)
Transmembrane
- ♦ P-gp (9)
- ♦ Proton Pump (16)
- ♦ GABA Receptor (23)
- ♦ Sodium Channel (43)
- ♦ Potassium Channel (40)
- ♦ Calcium Channel (56)
- ♦ ATPase (10)
- ♦ CRM1 (2)
- ♦ TRPV (0)
- ♦ CFTR (2)
- ♦ OCT (0)
- ♦ Amino Acid Transporter(1)
- ♦ Monocarboxylate Transporter(0)
- ♦ Apical Sodium-Dependent Bile Acid Transporter(1)
- ♦ Chloride Channel(3)
- ♦ GlyT(2)
- ♦ P2 Receptor(2)
- ♦ TRP Channel(19)
- ♦ BCRP(2)
- ♦ CD markers(2)
- ♦ HCN Channel(3)
- ♦ iGluR(12)
- ♦ Interleukins(1)
- ♦ nAChR(6)
- ♦ OAT(1)
- ♦ SGLT(2)
- ♦ Monocarboxylate Transporter(1)
- ♦ Adrenergic Receptor(1)
- ♦ P2X Receptor(1)
- ♦ CRAC Channel(2)
- ♦ Monoamine Transporter(2)
- ♦ Piezo Channel(1)
- ♦ Aquaporin(1)
- ♦ EAAT(1)
Endocrinology & Hormones
- ♦ Opioid Receptor (0)
- ♦ Glucocorticoid Receptor(8)
- ♦ Estrogen/progestogen Receptor (47)
- ♦ Androgen Receptor (18)
- ♦ RAAS (27)
- ♦ Aromatase(6)
- ♦ GPR(8)
- ♦ 5-alpha Reductase (2)
- ♦ Adrenergic Receptor(1)
- ♦ Mineralocorticoid Receptor(2)
- ♦ ACE(3)
- ♦ TSH Receptor(2)
- ♦ THR(1)
Microbiology
- ♦ HCV Protease (1)
- ♦ HIV Protease (2)
- ♦ CCR (2)
- ♦ Reverse Transcriptase(31)
- ♦ Integrase (0)
- ♦ Bacterial(12)
- ♦ Anti-infection(4)
- ♦ HSV(1)
- ♦ Influenza Virus(1)
- ♦ RSV(1)
- ♦ β-lactamase(1)
- ♦ Antibiotics(3)
- ♦ Antiviral(3)
- ♦ Parasite(6)
- ♦ Fungal(7)
- ♦ CMV(3)
- ♦ COVID-19(2)
Others
- ♦ IL Receptor (0)
- ♦ Biochemical Assay Reagents(12)
- ♦ Fluorescent Dye(30)
- ♦ Amino Acid Derivatives(1)
- ♦ gp120/CD4 (2)
- ♦ FXR(4)
- ♦ PKA (2)
- ♦ Thrombin (4)
- ♦ Liver X receptor (3)
- ♦ Others 1(364)
- ♦ Others 2(432)
- ♦ Others 3(332)
- ♦ Others 4(295)
- ♦ Others 5(250)
- ♦ Others 6(572)
- ♦ Others 7(235)
New Products
- ♦ New1(23635)
- ♦ New2(7157)
- ♦ New3(9979)
- ♦ New4(21)
Immunology/Inflammation
- ♦ STING(12)
- ♦ Glucocorticoid Receptor(7)
- ♦ Arginase(3)
- ♦ TLR(9)
- ♦ IRAK(4)
- ♦ Reactive Oxygen Species(13)
- ♦ ROS(4)
- ♦ COX(16)
- ♦ Prostaglandin Receptor(2)
- ♦ MIF(1)
- ♦ Nrf2(3)
- ♦ AKR1C(2)
- ♦ Antibiotics(1)
- ♦ Galectin(2)
- ♦ IFN(1)
- ♦ SPHK(4)
- ♦ Interleukins(4)
- ♦ NO Synthase(4)
- ♦ PGE synthase(4)
- ♦ SIK(1)
- ♦ Immunology & Inflammation related(8)
- ♦ PKR(1)
- ♦ PD-1/PD-L1(2)
- ♦ NLRP3(1)
- ♦ Complement System(2)
ADC Related
- ♦ ADC Linker(7)
- ♦ ADC Cytotoxin(4)
- ♦ Drug-Linker Conjugates for ADC(5)
Metabolic Enzyme/Protease
- ♦ Phosphodiesterase(PDE)(19)
- ♦ Aminopeptidase(2)
- ♦ Endogenous Metabolite(48)
- ♦ Phospholipase(5)
- ♦ ALDH(1)
- ♦ Cytochrome P450(9)
- ♦ Dipeptidyl Peptidase(2)
- ♦ Drug Metabolite(14)
- ♦ Farnesyl Transferase(2)
- ♦ HIF/HIF Prolyl-Hydroxylase(3)
- ♦ Lactate Dehydrogenase(2)
- ♦ Mitochondrial Metabolism(2)
- ♦ MMP(3)
- ♦ PAI-1(1)
- ♦ PDI(2)
- ♦ RAR/RXR(6)
- ♦ REV-ERB(1)
- ♦ ROR(2)
- ♦ Thrombin(3)
- ♦ 11β-HSD(2)
- ♦ MAGL(2)
- ♦ TrxR(1)
- ♦ Tyrosinase(3)
- ♦ Glucokinase(3)
- ♦ Phosphatase(5)
- ♦ Aldose Reductase(4)
- ♦ Carbonic Anhydrase(1)
- ♦ Epoxide Hydrolase(2)
- ♦ Mineralocorticoid Receptor(1)
- ♦ SCD(1)
- ♦ ACE(4)
- ♦ FXR(2)
- ♦ LXR(1)
- ♦ DGK(1)
- ♦ FTO(1)
- ♦ DHODH(1)
- ♦ HMGCR(1)
- ♦ FASN(4)
- ♦ Renin(2)
- ♦ Liposome(4)
- ♦ NADPH Oxidase(2)
- ♦ Glucosidase(4)
- ♦ HIV Protease(1)
- ♦ Factor Xa(1)
- ♦ Acyltransferase(1)
- ♦ Glutathione Peroxidase(1)
- ♦ Gutathione S-transferase(0)
- ♦ 5 alpha Reductase(1)
- ♦ Tryptophan Hydroxylase(1)
- ♦ Procollagen C Proteinase(1)
- ♦ Dopamine β-hydroxylase(1)
- ♦ NEDD8-activating Enzyme(1)
- ♦ Reactive Oxygen Species(1)
Anti-infection
- ♦ HSV(3)
- ♦ Fungal(20)
- ♦ Influenza Virus(17)
- ♦ Bacterial(117)
- ♦ HBV(6)
- ♦ HCV Protease(7)
- ♦ HIV(12)
- ♦ RABV(1)
- ♦ Parasite(12)
- ♦ Antibiotic(7)
- ♦ Reverse Transcriptase(2)
- ♦ Virus Protease(1)
- ♦ SARS-CoV(5)
- ♦ RSV(1)
Vitamin D Related/Nuclear Receptor
- ♦ Progesterone Receptor(7)
- ♦ Glucocorticoid Receptor(1)
- ♦ ERR(15)
- ♦ Thyroid Hormone Receptor(5)
- ♦ Androgen Receptor(3)
- ♦ VD/VDR(8)
PROTAC
- ♦ PROTAC Linkers(40)
- ♦ E3 Ligase Ligand-Linker Conjugates(8)
Unfolded Protein Response
- ♦ Deubiquitinase(1)
- ♦ IRE1(2)
- ♦ PDI(1)
- ♦ Eukaryotic Initiation Factor(1)

Product Type
Natural Products
- ♦ Natural Products 1(443)
Peptides
- ♦ Peptides 1(1969)
Antibodies
Amino Acids
- ♦ Amino Acids 1(384)
PROTACs
- ♦ PROTACs 1(33)
Fine Intermediates/Building Blocks
Others

Bulletin Board

Promegestone

Catalog No： V5585

CAS No. (CAS Registry Number)： 34184-77-5

Price： $0/g

Description: Promegestone (R-5020; RU-5020; trade name Surgestone) is a progestin medication and a synthetic progestogen acting as an agonist of the progesterone receptor. It has been used in me...

Prednisolone Phosphate Sodium

Catalog No： V5626

CAS No. (CAS Registry Number)： 125-02-0

Price： $0/g

Description: Prednisolone sodium phosphate is a water soluble form of prednisolone and a glucocorticoid with anti-inflammatory and immunomodulating properties. It is used to treat a variety of inflamm...

Endoxifen Z-isomer

Catalog No： V5719

CAS No. (CAS Registry Number)： 112093-28-4

Price： $0/g

Description: Endoxifen Z-isomer is an active metabolite of Tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen recep...

Sobetirome (GC1; QRX431)

Catalog No： V7512

CAS No. (CAS Registry Number)： 211110-63-3

Price： $0/g

Description: Sobetirome (GC-1; QRX-431) is a novel, potent and selective thyroid hormone receptor-beta (TRβ) agonist with cholesterol-lowering effects. It acts by binding selectively to...

AC-262536

Catalog No： V8411

CAS No. (CAS Registry Number)： 870888-46-3

Price： $0/g

Description: AC-262536 (AC262536) is a novel selective androgen receptor modulator (SARM) with beneficial anabolic effects. It has partial agonist activity with respect to testosterone and s...

Estradiol dipropionate

Catalog No： V11151

CAS No. (CAS Registry Number)： 113-38-2

Price： $0/g

Description: Estradiol dipropionate, specifically, 17-Beta-Estradiol-3,17-Dipropionate, is a semisynthetic, steroidal estrogen compound. References: Nestorović N, Trifunović S, Manojlović-S...

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