Topoisomerase - InvivoChem

location： Home > Products > Signaling Pathways > Cell Cycle > Topoisomerase

Signaling Pathways
Apoptosis
- ♦ Bcl-2(16)
- ♦ p53(11)
- ♦ Caspase(12)
- ♦ TNFa(13)
- ♦ Mdm2(17)
- ♦ c-RET(4)
- ♦ IAP(7)
- ♦ PERK(4)
- ♦ PD-1/PD-L1(15)
- ♦ Survivin(1)
- ♦ Apoptosis(12)
- ♦ RIP kinase(2)
- ♦ ROS(1)
- ♦ Cytohesin(1)
- ♦ Ras(1)
- ♦ Thymidylate Synthase(2)
- ♦ DAPK(1)
PI3K/Akt/mTOR
- ♦ PI3K (66)
- ♦ Akt (23)
- ♦ mTOR (23)
- ♦ GSK-3 (18)
- ♦ ATM/ATR (0)
- ♦ PDK-1 (4)
- ♦ S6 kinase (6)
- ♦ AMPK (12)
- ♦ DNA-PK (4)
- ♦ PTEN(1)
- ♦ PDPK1(1)
- ♦ NUDIX(1)
Epigenetics
- ♦ HDAC(4)
- ♦ HIF(7)
- ♦ PARP(0)
- ♦ JAK(37)
- ♦ Aurora Kinase(23)
- ♦ Histone Acetyltransferase (7)
- ♦ Histone Demethylase(10)
- ♦ Histone Methyltransferase (34)
- ♦ DNA Methyltransferase(8)
- ♦ Epigenetic Reader Domain (20)
- ♦ Sirtuin (13)
- ♦ Pim (6)
- ♦ PKC(4)
- ♦ SMYD(1)
- ♦ Methionine Adenosyltransferase(1)
- ♦ MicroRNA(1)
- ♦ AMPK(1)
MAPK
- ♦ MEK(18)
- ♦ ERK(14)
- ♦ Raf(18)
- ♦ JNK(13)
- ♦ p38 MAPK(19)
- ♦ RSK(1)
- ♦ Mixed Lineage Kinase(1)
Protein Tyrosine Kinase
- ♦ VEGFR (53)
- ♦ EGFR (47)
- ♦ PDGFR(15)
- ♦ c-MET (17)
- ♦ HER-2(2)
- ♦ ALK(11)
- ♦ FLT3 (9)
- ♦ FGFR (11)
- ♦ IFG-1R(10)
- ♦ c-Kit(5)
- ♦ Tie-2(1)
- ♦ CSF-1R(3)
- ♦ TAM Receptor (6)
- ♦ Trk receptor(3)
- ♦ c-RET(0)
- ♦ Axl(1)
- ♦ Bcr-Abl(3)
- ♦ Ephrin Receptor(1)
- ♦ Pyk2(1)
- ♦ c-Fms(2)
- ♦ DDR(1)
- ♦ FLT3(0)
- ♦ HER2(1)
- ♦ Src(1)
- ♦ Syk(1)
Angiogenesis
- ♦ VEGFR (1)
- ♦ EGFR (0)
- ♦ PDGFR (0)
- ♦ HIF (1)
- ♦ HER-2 (0)
- ♦ JAK (0)
- ♦ FLT3 (0)
- ♦ FGFR (0)
- ♦ BTK (8)
- ♦ Syk(6)
- ♦ FAK (8)
- ♦ Src (8)
- ♦ Bcr-Abl (10)
- ♦ VDA (3)
Proteases
- ♦ Proteasome (13)
- ♦ Cysteine Protease (11)
- ♦ Serine Protease(6)
- ♦ Gamma-secretase (10)
- ♦ HCV Protease (5)
- ♦ HIV Protease(7)
- ♦ MMP (6)
- ♦ DPP-4 (9)
- ♦ Caspase (0)
- ♦ Acyltransferase(1)
- ♦ Tyrosinase(1)
- ♦ Glutaminase(1)
- ♦ Thrombin(2)
NF-kB
- ♦ NOD1 (2)
- ♦ IκB/IKK(16)
- ♦ NF-κB(20)
- ♦ HDAC (0)
- ♦ ROS(1)
Autophagy
- ♦ Autophagy (29)
- ♦ LRRK2 (6)
JAK/STAT
- ♦ JAK (1)
- ♦ STAT(2)
- ♦ EGFR (3)
- ♦ Pim (1)
Metabolism
- ♦ PDE (28)
- ♦ P450 (e.g. CYP) (26)
- ♦ PPAR (17)
- ♦ Phospholipase (8)
- ♦ DHFR(6)
- ♦ Dehydrogenase (22)
- ♦ HSP (20)
- ♦ Carbonic Anhydrase (16)
- ♦ MAO (2)
- ♦ FAAH (6)
- ♦ CETP(4)
- ♦ Transferase (10)
- ♦ HMG-CoA Reductase(11)
- ♦ Hydroxylase (8)
- ♦ IDO (6)
- ♦ Retinoid Receptor (8)
- ♦ Factor Xa (4)
- ♦ AhR (3)
- ♦ Ferroptosis(3)
- ♦ Casein Kinase (6)
- ♦ NAMPT (3)
- ♦ Glucosylceramide Synthase(2)
- ♦ Aldose Reductase(1)
- ♦ ATP-citrate lyase(1)
- ♦ Carbohydrate Metabolism(1)
- ♦ FXR(2)
- ♦ IAP(1)
- ♦ Lipoxygenase(2)
- ♦ Mitochondrial Metabolism(1)
- ♦ PCSK9(1)
- ♦ Phosphorylase(1)
- ♦ Serine hydrolase(1)
- ♦ SGK(1)
- ♦ SCD(1)
- ♦ Vitamin(5)
- ♦ Acyltransferase(1)
- ♦ CAR(1)
- ♦ ROR(3)
- ♦ PRMT(1)
- ♦ PGC-1α(1)
- ♦ Lipase(1)
- ♦ OXPHOS(1)
- ♦ Peroxidases(1)
- ♦ Phosphatase(2)
- ♦ Decarboxylase(1)
- ♦ Prostaglandin Receptor(1)
- ♦ Serine/threonin kinase(1)
- ♦ Fatty Acid Synthase(3)
- ♦ THR(1)
Neuronal Signaling
- ♦ 5-HT Receptor (3)
- ♦ COX (40)
- ♦ GluR (20)
- ♦ Adrenergic Receptor(8)
- ♦ AChR Receptor (61)
- ♦ Histamine Receptor (4)
- ♦ Dopamine Receptor (6)
- ♦ Opioid Receptor (3)
- ♦ GABA Receptor (9)
- ♦ P-gp (0)
- ♦ CaMK (9)
- ♦ P2 Receptor (8)
- ♦ OX Receptor (1)
- ♦ MT Receptor (0)
- ♦ BACE (2)
- ♦ Gamma-secretase (0)
- ♦ Beta Amyloid (8)
- ♦ Monoamine Oxidase(1)
- ♦ P2Y Receptor(1)
- ♦ NMDAR(2)
- ♦ γ-secretase(1)
- ♦ Calcium Channel(1)
- ♦ Serotonin Transporter(1)
- ♦ Transthyretin (TTR)(1)
- ♦ Notch(1)
Ubiquitin
- ♦ E2 conjugating (1)
- ♦ p97 (3)
- ♦ E3 Ligase (0)
- ♦ DUB (11)
- ♦ Proteasome (0)
- ♦ E1 Activating(1)
Stem Cells/Wnt
- ♦ Hedgehog/Smoothened ROCK (1)
- ♦ ROCK(0)
- ♦ Wnt/beta-catenin (7)
- ♦ Gamma-secretase (0)
- ♦ Casein Kinase (3)
- ♦ TGF–beta/Smad (0)
- ♦ STAT (9)
- ♦ JAK (0)
- ♦ GSK-3 (0)
- ♦ Smo(1)
- ♦ PKA(1)
DNA Damage
- ♦ Telomerase(2)
- ♦ Topoisomerase (40)
- ♦ DNA/RNA Synthesis (74)
- ♦ HDAC (39)
- ♦ ATM/ATR (14)
- ♦ PARP (32)
- ♦ Sirtuin (0)
- ♦ DNA Stain(1)
- ♦ Nucleoside Antimetabolite/Analog(2)
- ♦ DNA alkylator(2)
- ♦ p97(1)
- ♦ CRISPR/Cas9(1)
- ♦ SMN(1)
GPCR & G Protein
- ♦ cAMP (2)
- ♦ Adenosine Receptor (23)
- ♦ Vasopressin Receptor (5)
- ♦ CXCR (8)
- ♦ CaSR (3)
- ♦ PAFR (2)
- ♦ CGRP Receptor (1)
- ♦ LPA Receptor (2)
- ♦ SGLT (5)
- ♦ S1P Receptor (9)
- ♦ Endothelin Receptor (8)
- ♦ Cannabinoid Receptor (11)
- ♦ 5-HT Receptor (85)
- ♦ Adrenergic Receptor (67)
- ♦ Histamine Receptor (49)
- ♦ Dopamine Receptor (46)
- ♦ Opioid Receptor (13)
- ♦ Hedgehog/Smoothened ROCK (11)
- ♦ OX Receptor (8)
- ♦ MT Receptor (2)
- ♦ Guanylate Cyclase(4)
- ♦ LPL Receptor(4)
- ♦ NPY receptor(1)
- ♦ Angiotensin Receptor(6)
- ♦ Free Fatty Acid Receptor(3)
- ♦ GnRH Receptor(3)
- ♦ GPR(2)
- ♦ Leukotriene Receptor(1)
- ♦ mAChR(7)
- ♦ Neurotensin Receptor(1)
- ♦ Prostaglandin Receptor(5)
- ♦ Sigma Receptor(1)
- ♦ PAR(1)
- ♦ CCR(1)
- ♦ GCGR(2)
- ♦ GHSR(2)
- ♦ GPCR19(1)
- ♦ LTR(1)
- ♦ mGluR(4)
- ♦ PKD(1)
- ♦ Ras(1)
- ♦ CCK receptor(1)
- ♦ Cholecystokinin Receptor(2)
- ♦ Formyl Peptide Receptor(1)
- ♦ G protein-coupled Bile Acid Receptor(1)
- ♦ Melanocortin Receptor(1)
- ♦ Neurokinin Receptor(1)
- ♦ Oxytocin Receptor(1)
- ♦ Somatostatin Receptor(1)
TGF-beta/Smad
- ♦ MT Receptor (20)
- ♦ Bcr-Abl (0)
- ♦ ROCK (20)
- ♦ PKC (10)
- ♦ TGF-β Receptor(5)
Cell Cycle
- ♦ CDK (47)
- ♦ Rho (14)
- ♦ PLK (11)
- ♦ Chk (6)
- ♦ Aurora Kinase (0)
- ♦ ROCK (2)
- ♦ PD-1/PD-L1 (0)
- ♦ c-Myc (3)
- ♦ Wee1 (1)
- ♦ APC (2)
- ♦ HSP(3)
- ♦ Microtubule/Tubulin(4)
- ♦ HDAC(2)
- ♦ PPAR(3)
- ♦ Eukaryotic Initiation Factor(1)
- ♦ Topoisomerase(1)
- ♦ Ras(1)
- ♦ Mps1(1)
- ♦ Kinesin(1)
- ♦ PAK(1)
- ♦ PERK(1)
Cytoskeletal Signaling
- ♦ Bcr-Abl(1)
- ♦ Wnt/beta-catenin (10)
- ♦ PKC (0)
- ♦ FAK(0)
- ♦ HSP (1)
- ♦ Dynamin (3)
- ♦ PAK (4)
- ♦ Integrin (11)
- ♦ Microtubule Associated(25)
- ♦ Kinesin (6)
Transmembrane
- ♦ P-gp (7)
- ♦ Proton Pump (11)
- ♦ GABA Receptor (18)
- ♦ Sodium Channel (38)
- ♦ Potassium Channel (26)
- ♦ Calcium Channel (43)
- ♦ ATPase (7)
- ♦ CRM1 (1)
- ♦ TRPV (0)
- ♦ CFTR (1)
- ♦ OCT (0)
- ♦ Amino Acid Transporter(1)
- ♦ Monocarboxylate Transporter(1)
- ♦ Apical Sodium-Dependent Bile Acid Transporter(1)
- ♦ Chloride Channel(3)
- ♦ GlyT(1)
- ♦ P2 Receptor(2)
- ♦ TRP Channel(14)
- ♦ BCRP(1)
- ♦ CD markers(1)
- ♦ HCN Channel(1)
- ♦ iGluR(3)
- ♦ Interleukins(1)
- ♦ nAChR(2)
- ♦ P-glycoprotein(0)
Endocrinology & Hormones
- ♦ Opioid Receptor (0)
- ♦ Glucocorticoid Receptor(6)
- ♦ Estrogen/progestogen Receptor (45)
- ♦ Androgen Receptor (17)
- ♦ RAAS (27)
- ♦ Aromatase(5)
- ♦ GPR(8)
- ♦ 5-alpha Reductase (2)
- ♦ Adrenergic Receptor(1)
- ♦ Mineralocorticoid Receptor(1)
- ♦ ACE(1)
Microbiology
- ♦ HCV Protease (1)
- ♦ HIV Protease (2)
- ♦ CCR (2)
- ♦ Reverse Transcriptase(30)
- ♦ Integrase (0)
- ♦ Bacterial(9)
- ♦ Anti-infection(3)
- ♦ HSV(1)
- ♦ Influenza Virus(1)
- ♦ RSV(1)
- ♦ β-lactamase(1)
- ♦ Antibiotics(3)
- ♦ Antiviral(3)
- ♦ Parasite(4)
- ♦ Fungal(5)
- ♦ CMV(1)
- ♦ COVID-19(1)
Others
- ♦ PKA (2)
- ♦ Thrombin (4)
- ♦ Liver X receptor (3)
- ♦ IL Receptor (0)
- ♦ Biochemical Assay Reagents(4)
- ♦ Fluorescent Dye(11)
- ♦ gp120/CD4 (2)
- ♦ FXR(4)
- ♦ Others 1(364)
- ♦ Others 2(433)
- ♦ Others 3(332)
- ♦ Others 4(295)
- ♦ Others 5(250)
- ♦ Others 6(572)
- ♦ Others 7(232)
New Products
- ♦ New1(24628)
- ♦ New2(7160)
- ♦ New3(9980)
- ♦ New4(21)
Immunology/Inflammation
- ♦ STING(3)
- ♦ Glucocorticoid Receptor(4)
- ♦ Arginase(3)
- ♦ TLR(5)
- ♦ IRAK(1)
- ♦ Reactive Oxygen Species(3)
- ♦ ROS(3)
- ♦ COX(9)
- ♦ Prostaglandin Receptor(2)
- ♦ MIF(1)
- ♦ Nrf2(2)
- ♦ AKR1C(1)
- ♦ Antibiotics(1)
- ♦ Galectin(1)
- ♦ IFN(1)
- ♦ SPHK(1)
- ♦ Interleukins(1)
- ♦ NO Synthase(1)
- ♦ PGE synthase(1)
- ♦ Reactive Oxygen Species(0)
- ♦ Immunology & Inflammation related(6)
ADC Related
- ♦ ADC Linker(7)
- ♦ ADC Cytotoxin(2)
Metabolic Enzyme/Protease
- ♦ Phosphodiesterase(PDE)(10)
- ♦ Aminopeptidase(1)
- ♦ Endogenous Metabolite(19)
- ♦ Phospholipase(1)
- ♦ ALDH(1)
- ♦ Cytochrome P450(3)
- ♦ Dipeptidyl Peptidase(1)
- ♦ Drug Metabolite(3)
- ♦ Farnesyl Transferase(1)
- ♦ HIF/HIF Prolyl-Hydroxylase(1)
- ♦ Lactate Dehydrogenase(1)
- ♦ Mitochondrial Metabolism(1)
- ♦ MMP(1)
- ♦ PAI-1(1)
- ♦ PDI(1)
- ♦ RAR/RXR(3)
- ♦ REV-ERB(1)
- ♦ ROR(1)
- ♦ Thrombin(1)
- ♦ 11β-HSD(2)
- ♦ MAGL(1)
- ♦ TrxR(1)
- ♦ Tyrosinase(2)
- ♦ Glucokinase(1)
- ♦ Phosphatase(2)
- ♦ Aldose Reductase(2)
- ♦ Carbonic Anhydrase(1)
- ♦ Epoxide Hydrolase(1)
- ♦ Mineralocorticoid Receptor(1)
- ♦ ACE(2)
- ♦ SCD(1)
Anti-infection
- ♦ HSV(3)
- ♦ Fungal(14)
- ♦ Influenza Virus(9)
- ♦ Bacterial(80)
- ♦ HBV(3)
- ♦ HCV Protease(5)
- ♦ HIV(7)
- ♦ RABV(1)
- ♦ Parasite(6)
- ♦ Antibiotic(3)
- ♦ Reverse Transcriptase(2)
- ♦ Virus Protease(1)
Vitamin D Related/Nuclear Receptor
- ♦ Progesterone Receptor(3)
- ♦ Glucocorticoid Receptor(1)
- ♦ ERR(2)
- ♦ Thyroid Hormone Receptor(2)
- ♦ Androgen Receptor(3)
- ♦ VD/VDR(3)
PROTAC
- ♦ PROTAC Linkers(40)
Cytoskeleton
- ♦ Gap Junction Protein(1)
- ♦ Myosin(1)

Product Type
Natural Products
- ♦ Natural Products 1(443)
Peptides
- ♦ Peptides 1(1960)
Antibodies
Amino Acids
- ♦ Amino Acids 1(384)
PROTACs
- ♦ PROTACs 1(29)
Fine Intermediates/Building Blocks
Others

Bulletin Board

Bisantrene HCl (CL-216942, NSC-337766)

Catalog No： V12770

CAS No. (CAS Registry Number)： 71439-68-4

Price： $0/g

Description: Bisantrene HCl (CL216942 and NSC337766), the hydrochloride salt of Bisantrene, is potent inhibitor of topoisomerase II and DNA intercalators with anticancer activity. It may be used ...

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