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    Catalog No: V0013
    CAS No. (CAS Registry Number): 881202-45-5
    Description: Serdemetan (formerly JNJ26854165; JNJ-26854165; JNJ 26854165), originally developed as an activator of p53, is now considered to be a novel, potent and orally bioactive antagonist of...
    Catalog No: V0014
    CAS No. (CAS Registry Number): 63208-82-2
    Description: Pifithrin-α ((PFTα) is a novel and potent inhibitor of p53, acting by inhibiting p53 protein transcription and p53-dependent transactivation of p53-responsive genes. It also act...
    Catalog No: V0015
    CAS No. (CAS Registry Number): 213261-59-7
    Description: RITA (also known as NSC-652287) is a novel and potent inhibitor of p53-HDM-2 protein-protein interaction with potential anticancer activity. It binds to p53dN with a Kd of 1.5 nM, an...
    Catalog No: V0016
    CAS No. (CAS Registry Number): 380315-80-0
    Description: Tenovin-1, a small molecule compound discovered by a cell-based screen, is a novel and potent activator of p53 that protects against MDM2-mediated p53 degradation. It acts by inhibit...
    Catalog No: V0017
    CAS No. (CAS Registry Number): 71555-25-4
    Description: NSC319726 is a novel and potent p53(R175) mutant reactivator with with potential anticancer activity. It exhibits growth inhibition in cells expressing mutant p53 (IC50 of 8 nM ...
    Catalog No: V0018
    CAS No. (CAS Registry Number): 803647-40-7
    Description: NSC59984 is a novel and potent activator of p53 with potential anticancer activity. It acts via induction of mutant p53 protein degradation and p73 activation. References: ...
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