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    Catalog No: V1001
    CAS No. (CAS Registry Number): 918504-65-1
    Description: Vemurafenib (formerly also known as PLX4032, RG7204) is a potent and selective inhibitor of B-RafV600E with IC50 of 31 nM in enzymatic assay. Vemurafenib is an orally bioavailab...
    Catalog No: V1002
    CAS No. (CAS Registry Number): 918505-84-7
    Description: PLX4720, a 7-azaindole derivative discovered by a structure-guided discovery approach, is a novel, potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free...
    Catalog No: V1003
    CAS No. (CAS Registry Number): 475207-59-1
    Description: Sorafenib Tosylate (also known as BAY 43-9006 Tosylate) is a potent multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM in enzymatic assays, res...
    Catalog No: V1004
    CAS No. (CAS Registry Number): 1195765-45-7
    Description: Dabrafenib (formerly known as GSK2118436; GSK2118436A) is a novel, specific, orally bioavailable inhibitor of BRAF V600 mutants with IC50 of 0.8 nM in cell-free assays and is 4-...
    Catalog No: V1005
    CAS No. (CAS Registry Number): 905281-76-7
    Description: GDC-0879 is a novel, potent, highly selective, and orally bioavailable B-Raf inhibitor with IC50 of 0.13 nM in A375 and Colo205 cells. In mice treated with GDC-0879, both cell line- ...
    Catalog No: V1006
    CAS No. (CAS Registry Number): 878739-06-1
    Description: AZ-628 is a novel, selective, orally bioavailable Raf inhibitor with excellent pharmacokinetic properties and robust tumor growth inhibition in xenograft studies with IC50 values...
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