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    Catalog No: V0146
    CAS No. (CAS Registry Number): 1394076-92-6
    Description: GNE-317 is a novel, potent, blood-brain barrier (BBB) penetrant and selective PI3K inhibitor with potential anticancer activity. GNE-317 targets the PI3K pathway and can cross the Blood-B...
    Catalog No: V0147
    CAS No. (CAS Registry Number): 117-39-5
    Description: Quercetin, a naturally accuring flavonoid found in vegetables, fruit and wine, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4-5.4 μM. A number of reports ...
    Catalog No: V0148
    CAS No. (CAS Registry Number): 1276110-06-5
    Description: HS-173 is a novel and potent PI3Kα (phosphatidylinositol 3-kinase) inhibitor with IC50 of 0.8 nM. HS-173 has potential anticancer activity by promoting apoptosis and inhibiting angiogenes...
    Catalog No: V0149
    CAS No. (CAS Registry Number): 955977-50-1
    Description: PI-3065 is a selective p110δ inhibitor with IC50 of 15 nM, and 70-fold selectivity over other PI3K family members. PI-3065 has been reported to selectively inhibit p110δkinase with Ki val...
    Catalog No: V0150
    CAS No. (CAS Registry Number): 934526-89-3
    Description: Pilaralisib (formerly XL147) is a novel, potent, selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ with IC50 of 39 nM/36 nM/23 nM in cell-free assays, less potent to PI3Kβ. Pi...
    Catalog No: V0151
    CAS No. (CAS Registry Number): 1276553-09-3
    Description: PF-4989216 is a novel, potent and selective small molecule PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for isoforms p110α, p110β, p110γ, p110δ, and VPS34, respective...
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