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      Nemiralisib (GSK2269557)
      Nemiralisib (GSK2269557)
      Catalog No： V2539
      CAS No. (CAS Registry Number)： 1254036-71-9
      Description: Nemiralisib (GSK-2269557) is a novel, potent and selective PI3Kδ inhibitor with pKi of 9.9. It is active in a disease relevant brown Norway rat acute OVA model of Th2-driven lung inflamma...
      740 Y-P (PDGFR 740Y-P)
      740 Y-P (PDGFR 740Y-P)
      Catalog No： V2540
      CAS No. (CAS Registry Number)： 1236188-16-1
      Description: 740 Y-P is a cell-permeable peptide acting as a phosphopeptide activator of PI3K. 740 Y-P plays an important role in PI3K/AKT signaling pathway. When tested with human melanoma MNT-1 cell...
      GDC-0084 (Paxalisib; RG7666)
      GDC-0084 (Paxalisib; RG7666)
      Catalog No： V2541
      CAS No. (CAS Registry Number)： 1382979-44-3
      Description: GDC-0084 (Paxalisib; RG7666) is a novel, potent and brain penetrant inhibitor of phosphatidylinositol 3-kinase (PI3K) and mTOR with potential antineoplastic activity. It has Ki values of ...
      CZ415
      CZ415
      Catalog No： V2542
      CAS No. (CAS Registry Number)： 1429639-50-8
      Description: CZ415 is a potent, cell-permeable (Kd app = 6.9 nM), and ATP-competitive mTOR inhibitor with high selectivity over any other kinase (IC50 = 14.5 nM IC50 for pS6RP and 14.8 nM for pAKT) an...
      Deguelin
      Deguelin
      Catalog No： V2543
      CAS No. (CAS Registry Number)： 522-17-8
      Description: Deguelin [(-)-Deguelin, (-)-cis-Deguelin], a naturally occurring rotenoid isolated from plants in the Mundulea sericea family, is an Akt inhibitor with anti-tumor effect on several cancer...
      AZD8835
      AZD8835
      Catalog No： V2544
      CAS No. (CAS Registry Number)： 1620576-64-8
      Description: AZD8835 is a novel, selective, and orally bioavailable inhibitor of the class I (PI3K) catalytic subunit alpha (PIK3CA) PI3Kα and PI3Kδ with IC50s of 6.2 and 5.7 nM, respectively with pot...
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