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    Catalog No: V4442
    CAS No. (CAS Registry Number): 1818339-66-0 (free base)
    Description: PF-06751979 is a novel, highly potent, brain penetrant, and selective inhibitor of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) with an IC50 of 7.3 nM in BACE1 bin...
    Catalog No: V4443
    CAS No. (CAS Registry Number): 1020315-31-4
    Description: PF-04457845 is a novel, highly potent and selective FAAH (fatty acid amide hydrolase) inhibitor with IC50 values of 7.2±0.63 nM and 7.4±0.62 nM for ...
    Catalog No: V4444
    CAS No. (CAS Registry Number): 1219633-99-4
    Description: PF-4778574 is a novel and potent positive allosteric modulation (PAM) of AMPA receptor with EC50 of 45 to 919 nM in differenct cells. Working memory impairme...
    Catalog No: V4445
    CAS No. (CAS Registry Number): 1407966-77-1
    Description: PF-06465469 is a novel, potent and covalent inhibitor of ITK (IL-2 inducible T-cell kinase) with an IC50 of 2 nM. ITK is expressed primarily in immune cells,...
    Catalog No: V4446
    CAS No. (CAS Registry Number): 77307-50-7
    Description: SL0101 (SL 0101-1) a kaempferol glycoside isolated from the tropical plant F. refracta, is a novel, potent, cell-permeable, selective, reversible, ATP-competitive p90 ...
    Catalog No: V4447
    CAS No. (CAS Registry Number): 1394033-54-5
    Description: PF-05180999 is a phosphodiesterase 2A (PDE2A) inhibitor, with an IC50 of 1.6 nM. PF-05180999 was identified as a preclinical candidate targeting cognitive im...
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