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    Catalog No: V4542
    CAS No. (CAS Registry Number): 149709-44-4
    Description: Sacubitrilat (also known as LBQ-657) is the activated form of Sacubitril hemicalcium (also known as AHU-377 hemicalcium) which is a novel and potent NEP (neutral endopeptidase 24.11)...
    Catalog No: V4543
    CAS No. (CAS Registry Number): 1199590-75-4
    Description: GNE-220 is a novel, potent and selective inhibitor of MAP4K4 with an IC50 of 7 nM. Cell migration is a stepwise process that coordinates multiple molecular m...
    Catalog No: V4544
    CAS No. (CAS Registry Number): 1199590-75-4 (free base)
    Description: GNE-220 HCl is a novel, potent and selective inhibitor of MAP4K4 with an IC50 of 7 nM. Cell migration is a stepwise process that coordinates multiple molecul...
    Catalog No: V4545
    CAS No. (CAS Registry Number): 1809794-70-4 (racemic)
    Description: GNE-140 racemate is a novel and potent lactate dehydrogenase (LDHA) inhibitor which is a racemic mixture of (R)-GNE-140 and (S)-GNE-140. Metabolic reprogramming in tumors represents ...
    Catalog No: V4546
    CAS No. (CAS Registry Number): 2003234-63-5 (R-isomer)
    Description: (R)-GNE-140, the S-enantiomer of GNE-140, is a novel and potent lactate dehydrogenase (LDHA) inhibitor with IC50s of 3 nM and 5 nM for LDHA and LDHB, respectively. Metabolic rep...
    Catalog No: V4547
    CAS No. (CAS Registry Number): 2003234-64-6
    Description: (S)-GNE-140, the S-enantiomer of GNE-140, is a novel and potent lactate dehydrogenase (LDHA) inhibitor with less activity. Metabolic reprogramming in tumors represents a potential th...
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