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    Catalog No: V0457
    CAS No. (CAS Registry Number): 334949-59-6
    Description: BIX02188 (BIX-02188), an indolinone analog, is a novel, highly potent and selective MEK5 inhibitor with the potential to relieve neuropathic pain. It inhibits MEK5 with IC50 of 4.3 n...
    Catalog No: V0458
    CAS No. (CAS Registry Number): 869357-68-6
    Description: AZD8330 (AZD-8330; ARRY-704; ARRY-424704) is an orally bioactive and non-ATP competitive (Allosteric) MEK 1/2 inhibitor with potential anticancer activity. It inhibits MEK1/2 wi...
    Catalog No: V0459
    CAS No. (CAS Registry Number): 1035555-63-5
    Description: TAK-733 is a novel, potent, selective and orally bioavailable allosteric (non-ATP competitive) inhibitor of MEK with potential anticancer activity. It inhibits MEK with an IC50 of 3....
    Catalog No: V0460
    CAS No. (CAS Registry Number): 391210-00-7
    Description: PD318088 (PD-318088), an analog of PD184352, is a novel, potent and non-ATP competitive (allosteric) MEK1/2 inhibitor with potential anticancer activity. PD318088 has high anti-proliferat...
    Catalog No: V0461
    CAS No. (CAS Registry Number): 923032-37-5
    Description: Refametinib (formerly RDEA-119, BAY 86-9766) is an orally bioavailable, highly selective and non-ATP-competitive (allosteric) inhibitor of MEK1/2 with potential antitumor activity. It inh...
    Catalog No: V0463
    CAS No. (CAS Registry Number): 942183-80-4
    Description: SCH772984 (SCH-772984) is a novel, potent and ATP-competitive inhibitor of ERK1/2 with potential antitumor activity. It inhibits ERK1/2 with IC50s of 4 nM and 1 nM in cell-free assay, res...
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