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    Catalog No: V0457
    CAS No. (CAS Registry Number): 334949-59-6
    Description: BIX02188 is a novel, highly potent and selective inhibitor of MEK5 with IC50 of 4.3 nM, it also inhibits ERK5 catalytic activity with IC50 of 810 nM, and does not inhibit closely rel...
    Catalog No: V0458
    CAS No. (CAS Registry Number): 869357-68-6
    Description: AZD8330 (also known as ARRY704 and ARRY424704) is a novel, potent, selective, orally bioactive and non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. It is orally bioavailable ...
    Catalog No: V0459
    CAS No. (CAS Registry Number): 1035555-63-5
    Description: TAK-733 is a novel, potent, selective and orally bioavailable allosteric inhibitor of MEK with IC50 of 3.2 nM for MEK1, it is inactive to Abl1, AKT3, c-RAF, CamK1, CDK2, c-Met, etc. ...
    Catalog No: V0460
    CAS No. (CAS Registry Number): 391210-00-7
    Description: PD318088 is a novel, potent and non-ATP competitive / allosteric MEK1/2 inhibitor which binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-bindi...
    Catalog No: V0461
    CAS No. (CAS Registry Number): 923032-37-5
    Description: Refametinib (formerly also known as RDEA119, BAY 86-9766) is a novel, highly potent, orally bioavailable, ATP non-competitive (allosteric) and highly selective inhibitor of MEK1 and ...
    Catalog No: V0463
    CAS No. (CAS Registry Number): 942183-80-4
    Description: SCH772984 is a novel, potent and ATP-competitive iinhibitor of ERK1/2 with IC50 of 4 nM and 1 nM in cell-free assay, respectively. SCH772984 was identified by an affinity-based mass ...
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