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    Catalog No: V0450
    CAS No. (CAS Registry Number): 1094614-85-3
    Description: BIX02189 is a novel, potent and selective inhibitor of MEK5 with IC50 value of 1.5 nM, it also inhibits ERK5 catalytic activity with IC50 of 59 nM in cell-free assays; but it does no...
    Catalog No: V0451
    CAS No. (CAS Registry Number): 1168091-68-6
    Description: GDC-0623 is a novel, potent, orally bioactive, selective and ATP-uncompetitive (allosteric) MEK1 inhibitor with Ki of 0.13 nM. GDC-0623 has efficacy against both mutant BRAF and mutant KR...
    Catalog No: V0453
    CAS No. (CAS Registry Number): 934660-93-2 (free base)
    Description: Cobimetinib (formerly also known as GDC-0973, RG7420 or XL-518)  is a novel, orally bioavailable, highly potent and selective small-molecule MEK1 inhibitor with IC50 of 4.2 nM. It is...
    Catalog No: V0454
    CAS No. (CAS Registry Number): 606143-89-9
    Description: Binimetinib (formerly known as MEK162, ARRY-162, ARRY-438162; trade name: Mektovi) is a novel potent, highly selective and orally bioavailable inhibitor of MEK1/2 with IC50 of 12 nM ...
    Catalog No: V0455
    CAS No. (CAS Registry Number): 1236699-92-5
    Description: Pimasertib (formerly also known as AS703026, SAR245509, MSC1936369B) is a novel, highly selective, potent, and  non-ATP competitive / allosteric inhibitor of MEK1/2 with IC50 of 5 nM...
    Catalog No: V0456
    CAS No. (CAS Registry Number): 305350-87-2
    Description: SL327 (SL-327) is a novel, potent and selective inhibitor for MEK1/2 with IC50 of 0.18 μM/ 0.22μM, it has no activity towards Erk1, MKK3, MKK4, c-JUN, PKC, PKA, or CamKII. SL327 blocks ac...
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