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    Catalog No: V0450
    CAS No. (CAS Registry Number): 1094614-85-3
    Description: BIX02189 is a novel, potent and selective inhibitor of MEK5 with important biological activity. It inhibits MEK5 with an IC50 of 1.5 nM. It also inhibits ERK5 with an IC50 of 59 nM i...
    Catalog No: V0451
    CAS No. (CAS Registry Number): 1168091-68-6
    Description: GDC-0623 (G868) is a novel, potent, orally bioactive, selective and non-ATP-competitive (allosteric) inhibitor of MEK1 with potential anticancer activity. It inhibits MEK1 with a Ki ...
    Catalog No: V0453
    CAS No. (CAS Registry Number): 934660-93-2 (free base)
    Description: Cobimetinib (formerly GDC0973, RG7420, XL518; trade name Cotellic) is an orally bioavailable and selective small-molecule inhibitor of MEK1 with potential anticancer activity. It inhibits...
    Catalog No: V0454
    CAS No. (CAS Registry Number): 606143-89-9
    Description: Binimetinib (trade name: Mektovi; formerly ARRY-438162; ARRY-162; MEK-162) is a highly selective and orally bioavailable MEK1/2 (mitogen-activated protein kinase kinase) inhibit...
    Catalog No: V0455
    CAS No. (CAS Registry Number): 1236699-92-5
    Description: Pimasertib (formerly SAR-245509, AS-703026, MSC-1936369B) is a selective, orally bioavailable and  non-ATP competitive (allosteric) inhibitor of MEK1/2 with potential anticancer...
    Catalog No: V0456
    CAS No. (CAS Registry Number): 305350-87-2
    Description: SL327 (SL-327) is a novel, potent and selective inhibitor for MEK1/2 with the ability to cross blood brain barrier and block fear conditioning. It inhibits MEK1/2 with IC50...
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