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    Catalog No: V0051
    CAS No. (CAS Registry Number): 1260251-31-7
    Description: Birinapant (TL32711; TL-32711; TL 32711) is a novel and potent bivalent SMAC peptido-mimetic antagonist, mostly to cIAP1 with Kd ofReferences: Breast Cancer Res Treat. 2013 Jan;...
    Catalog No: V0052
    CAS No. (CAS Registry Number): 873652-48-3 (free base);
    Description: GDC-0152 (RG-7419) is a novel and potent antagonist of XIAP-BIR3, ML-IAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 28 nM, 14 nM, 17 nM and 43 nM in cell-free assays, respectively; less a...
    Catalog No: V0053
    CAS No. (CAS Registry Number): 1071992-99-8 (free base)
    Description: AT406 (also known as SM-406, ARRY-334543) is a novel, potent and orally bioavailable Smac/DIABLO mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase)....
    Catalog No: V0054
    CAS No. (CAS Registry Number): 550-24-3
    Description: Embelin, a naturally occuring quinone compound isolated from the Japanese Ardisia herb, is a potent and cell-permeable inhibitor of X-linked inhibitor of apoptosis (XIAP) with I...
    Catalog No: V0055
    CAS No. (CAS Registry Number): 1001600-56-1
    Description: BV-6 is a SMAC mimetic compound, a dual cIAP (inhibitor of apoptosis) and XIAP inhibitor, acting by promoting glioblastoma cancer stem-like cell differentiation by activating NF-κB. ...
    Catalog No: V0056
    CAS No. (CAS Registry Number): 1005342-46-0
    Description: LCL161 is a novel SMAC mimetic compound which potently binds to and inhibits multiple IAPs (i.e. XIAP, c-IAP), it inhibits XIAP in HEK293 cell and cIAP1 in M...
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